Prognostic Value of Left Ventricular Mass Index in Obstructive Hypertrophic Cardiomyopathy Undergoing Septal Myectomy

Changrong Nie1 site in 1 country490 target enrollmentJune 1, 2011

ConditionsObstructive Hypertrophic Cardiomyopathy (oHCM)

Overview

Phase: N/A
Intervention: Not specified
Conditions: Obstructive Hypertrophic Cardiomyopathy (oHCM)
Sponsor: Changrong Nie
Enrollment: 490
Locations: 1
Primary Endpoint: All-cause death
Status: Completed
Last Updated: last year

Overview Investigators Eligibility Criteria Outcomes Sites Similar Trials

Overview

Brief Summary

In this study, we aimed to analyze the association between left ventricular mass index and clinical outcomes to provide the potential indicator for worse survival.

Detailed Description

This retrospective study aimed to determine the prognostic value of left ventricular mass index in predicting clinical outcomes, including all-cause death, new-onset or recurrent atrial fibrillation, and a composite endpoint of all-cause death, heart failure,permanent pacemaker implantation, new-onset or recurrent atrial fibrillation, and stroke.

Registry

clinicaltrials.gov

Start Date

June 1, 2011

End Date

December 31, 2020

Last Updated

last year

Study Type

Observational

Sex

All

Investigators

Sponsor

Changrong Nie

Responsible Party

Sponsor Investigator

Principal Investigator

Changrong Nie

Chinese Academy of Medical Sciences, Fuwai Hospital

Eligibility Criteria

Inclusion Criteria

•(1) Difficulty in relieving symptoms with medication or recurrent syncope. (2) Left ventricular outflow tract (LVOT) pressure gradient ≥ 50 mmHg at rest or with provocation and the maximum thickness of the septum is ≧ 15 mm.

Exclusion Criteria

•(1) Combined right ventricular outflow tract obstruction requiring right ventricular outflow tract dissection. (2) Combined mitral or aortic valve organic lesions requiring valve replacement surgery. (3) Apical ventricular aneurysm formation requiring ventriculotomy. (4) Previous septal reduction therapy, including alcohol ablation or septal myectomy. (5) patients did not undergo cardiac magnetic resonance examination.