A Prospective randomized comparative study evaluating the analgesic efficacy of 0.2% Ropivacaine versus 0.2% Ropivacaine with dexmedetomidine in adductor canal block combined with iPACK for total knee arthroplasty
试验速览
- 阶段
- Unknown
- 状态
- 尚未招募
- 发起方
- 入组人数
- 30
- 试验地点
- 1
- 主要终点
- Duration of Analgesia
研究概览
简要总结
This is a prospective randomized comparative interventional study designed to evaluate the analgesic efficacy of 0.2percentageropivacaine alone versus 0.2 percentage ropivacaine combined with dexmedetomidine when used in adductor canal block combined with iPACK infiltration between the popliteal artery and capsule of the knee for postoperative analgesia in patients undergoing total knee arthroplasty TKA
Patients undergoing unilateral TKA will be randomly assigned to one of two groups
Group R Receiving 0.2percentage ropivacaine
Group RD Receiving 0.2 percentage ropivacaine with dexmedetomidine
Both groups will receive the block as part of a multimodal analgesic regimen The primary outcome is to compare the duration and quality of postoperative analgesia between the two groups Secondary outcomes include opioid consumption pain scores patient satisfaction and incidence of adverse effects
This study aims to determine whether the addition of dexmedetomidine enhances the analgesic effect of ropivacaine in regional nerve blocks for knee arthroplasty potentially improving pain control and functional recovery
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 盲法
- Participant and Outcome Assessor Blinded
入排标准
- 年龄范围
- 25.00 Year(s) 至 80.00 Year(s)（—）
- 性别
- All
入选标准
- •Adults aged 25-80 years ASA physical status I–III Undergoing elective total knee replacement surgeries Willingness to participate with informed consent.
排除标准
- •Patient refusal to the study BMI morethan 40 Revision or bilateral knee surgeries Known allergy to local anaesthetics Neurological disorders affecting lower limb mobility Coagulopathy or on anticoagulants Patients refusing regional anaesthesia.
结局指标
主要结局
Duration of Analgesia
时间窗: Duration of Analgesia
次要结局
- Postoperative pain scores using the NRS at rest & during movement at 2 4 6 12 24 36 & 48 hours(Time of activation of first epidural as rescue analgesic)
研究者
PRAVEEN RAJU
Ballari Medical college and Research centre