Added Value of N Acetyle Cysteine to Clomiphene Citrate in PCO

Not Applicable

Completed

• Conditions: PCO
• Interventions: Drug: clomiphene citrate plus metformin; Drug: Clomiphene plus metformin plus N acetyle cysteine in arm number 1; Drug: Clomiphene citrate plus metformin with chromium

• Registration Number: NCT04170439
• Lead Sponsor: Aljazeera Hospital

Brief Summary

PCO is one of the factors associated with delayed conception

Detailed Description

In an attempt to induce ovulation Clomiphene citrate can be given in conjunction with N acetyle cysteine

Study Timeline

• Study First Submitted: 2019-11-16
• Study First Submitted QC: 2019-11-19
• Study Start: 2019-11-20
• Study First Posted: 2019-11-20
• Primary Completion: 2020-05-02
• Study Completion: 2020-05-15
• Status Verified: 2021-04
• Last Update Submitted: 2021-04-26
• Last Update Posted: 2021-04-28

Recruitment & Eligibility

• Status: COMPLETED
• Sex: Female
• Target Recruitment: 108

Inclusion Criteria

• women with PCO

Exclusion Criteria

• women who donot have PCO

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
clomiphen citrate plus metformin	clomiphene citrate plus metformin	Women who will receive clomiphene plus metformin
clomiphene plus metformin plus N acetyle cysteine	Clomiphene plus metformin plus N acetyle cysteine in arm number 1	Women who will receive clomiphene citrate plus metformin plus n acetyle cysteine
clomiphene plus metformin plus chromium	Clomiphene citrate plus metformin with chromium	Women who will receive clomiphene plus metformin plus chromium

Primary Outcome Measures

Name	Time	Method
The number of women who will have mature follicles wih their size and number of mqture follicles The number of women who will have mature follicles	within 2 weeks	Assessment of women in both groups for size and number of follicles

Trial Locations

Locations (2)

Algazeerah and Kasralainy hospital; 🇪🇬 Giza, Egypt

Algazeerah; 🇪🇬 Giza, Egypt