NCT04959526招募中不适用
Comparison of Shear-wave Elastography to State-of-the-art Respiratory Function Testing to Measure the Range of Forces Generated by the Diaphragm Muscle
适应症
干预措施
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 发起方
- Mayo Clinic
- 入组人数
- 24
- 试验地点
- 1
- 主要终点
- Shear wave speed
研究概览
简要总结
The purpose of this study is to evaluate the relationship between transdiaphragmatic pressure (Pdi) and diaphragm shear-wave elastography (SWE) during state-of-the-art respiratory muscle testing including volitional efforts (e.g., maximal inspiratory pressure, maximal expiratory pressure, Valsalva maneuver), as well as maximal phrenic nerve stimulation.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Basic Science
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •- Adult male and female healthy volunteers.
排除标准
- •Volunteers who are pregnant.
- •Volunteers with known pulmonary pathology (COPD, asthma requiring routine treatment).
研究组 & 干预措施
Respiratory Function Testing
Experimental
All subjects will receive standard respiratory function testing and ultrasound-based elastography measurements across various behaviors and conditions
干预措施: Shear-wave elastography (Diagnostic Test)
结局指标
主要结局
Shear wave speed
时间窗: 3 hours
Elastography of the diaphragm muscle across various behaviors and conditions
次要结局
未报告次要终点
研究者
Carlos B Mantilla, MD, PhD
Principal Investigator
Mayo Clinic
研究点 (1)
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