Integrative Study of Vestibular Pathology
- Conditions
- Dizziness; Syndrome
- Interventions
- Other: Neurosensory
- Registration Number
- NCT05525728
- Lead Sponsor
- University Hospital, Caen
- Brief Summary
Exploratory posturological, neurosensory, cognitive, emotional, personality and general evaluations (quality of life).
The investigators will characterize a sensory profile quantified by one or more scores from a multi-parameter baysian approach. Each parameter and these scores will be correlated to the type of vestibular damage and its recovery in order to establish diagnostic, prognostic and therapeutic follow-up markers.
- Detailed Description
This is an exploratory neurophysiological work that aims to identify diagnostic, prognostic and therapeutic markers in vestibular pathology.
Theinvestigators wish to characterize the neurosensory profile of individuals using new exploration paradigms provided by a new posturology platform coupled with virtual reality scenarios and by proposing a complete transversal approach in terms of evaluation of the subjects: personality, cognition, emotion including the depressive state, sensory strategy, general data.
Baysian statistical approaches and linear mixed model will be used to determine markers of sensory profile correlated to the vestibular damage for diagnostic, prognostic and therapeutic follow-up.
The investigators aim to be able to better characterize the cognitive-emotional and sensory deficits expressed by the vertiginous and unstable patients, to integrate it into the evaluation of the vestibular pathology, to use these markers to better discriminate the underlying physiopathological mechanisms, and to improve at the same time the diagnosis of the functional attack and the rehabilitation follow-up of the patients.
Recruitment & Eligibility
- Status
- RECRUITING
- Sex
- All
- Target Recruitment
- 80
- Male or female patient (18-80 years old)
- Patient with an acute or chronic vestibular pathology according to ENT diagnostic criteria
- Subjects under 18 years of age
- Pregnant or breastfeeding women,
- Persons in an emergency situation or unable to give their consent, including adults under guardianship
- Person under legal protection
- Patient presenting a vertigo or postural disorders of non vestibular etiology
- Persons deprived of liberty, minors, protected adults,
- Patients with an intercurrent neurological pathology including cerebellar pathology
- Inclusion of the subject in another interventional research protocol with pharmacological aim during the present study
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- SINGLE_GROUP
- Arm && Interventions
Group Intervention Description patient Neurosensory One cohort of patients
- Primary Outcome Measures
Name Time Method Cognition through follow-up, an average of 6 months Spatial cognitive performance in a calibrated virtual radial maze
Posture through follow-up, an average of 6 months postural measurement
Personnality characteristic through follow-up, an average of 6 months Evaluation of the BIg Five inventory test
Sleep through follow-up, an average of 6 months Quantitative sleep recording
Emotion through follow-up, an average of 6 months Anxiety measurement via questionnary
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (2)
Frédéric Xavier
🇫🇷Vitrolles, France
Caen University Hospital
🇫🇷Caen, France