Pharmacokinetic study to assess the bioavailability of the cocoa flavanols catechin and epicatechin from different matrices.
Completed
- Conditions
- cardiovascular disease1008220610047079
- Registration Number
- NL-OMON35796
- Lead Sponsor
- Callebaut NV
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 10
Inclusion Criteria
-Adults between 20 and 45 years old
-Non*smoking individuals
-Capable and willing to sign the Informed Consent Form at voluntary basis
-Considered healthy based on their medical history as questioned by the investigator during an interview and a general physical examination by the investigator
-Female volunteers do not intend to become pregnant prior to or during the study and using adequate contraception
Exclusion Criteria
-Clinically significant abnormal liver biochemistry
-Clinically significant abnormal serum creatinin
-Abnormal body mass index
-Use of concomitant medications or supplements
-Blood donation during the last 4 weeks prior to the first dosing till 4 weeks after the last dosing
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <p>Area under the blood concetration - time curve (AUC).</p><br>
- Secondary Outcome Measures
Name Time Method <p>Maximal blood concentration (Cmax) and time to maximal blood concentration<br /><br>(Tmax).</p><br>