Oxidative Stress is Associated with Impaired Cardiac Autonomic Control and Lung Function in COPD Patients

Faculty of Medicine, Khon Kaen University0 个研究点目标入组 100 人开始时间: 2016年6月7日最近更新: 2024年8月19日

适应症

试验速览

暂无简介。

•Group 1. The diagnosis of COPD and its severity were determined using the Global Initiative for Chronic Obstructive Lung Disease (GOLD) 2015 guidelines [1]. COPD patients with GOLD stage I (FEV1 â‰¥ 80% predicted), II (50% ï‚£ FEV1 < 80% predicted), III (30% ï‚£ FEV1 < 50% predicted), and IV (FEV1 < 30% predicted) numbered 14, 19, 16, and 1 patients, respectively. None of the COPD patients had COPD exacerbation within the three months prior to the start of the study.
•Group 2. non-smoking healthy male controls

•Subjects meeting any of the following criteria were excluded from the study: history of cardiac arrhythmias or potential ECG alterations, history consistent with heart disease, diabetes mellitus, hypertension or other concomitant respiratory diseases, central or peripheral nervous system diseases, and electrolyte imbalance.

发起方

Faculty of Medicine, Khon Kaen University