The Effect of Burst-suppression-pattern in EEG on Generating Somatosensory Evoked Potentials
试验速览
- 阶段
- 不适用
- 发起方
- 入组人数
- 60
- 试验地点
- 1
- 主要终点
- SEP ampiltude in burst-suppression-EEG
研究概览
简要总结
The relation between burst and suppression periods in transcranial and direct cortical recorded EEG with cortical amplitudes median nerve somatosensory evoked potentials is studied.
60 patients are included in this study: 15 patients undergoing brain tumor surgery, 15 spine surgery (University Hospital Düsseldorf) and 30 patients during general surgical procedures (Helios Klinikum Wuppertal).
研究设计
- 研究类型
- Interventional
- 分配方式
- Non Randomized
- 干预模型
- Parallel
- 主要目的
- Basic Science
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Location Helios Klinikum Wuppertal: neurological healthy patients, which undergo an elective surgery under general anaesthesia
- •Location Department of Neurosurgery, University Hospital Düsseldorf: all patients with intracranial interventions and the possibility to place a stripe electrode without complications on cortex (it is decided by the surgeon while surgery because of the situs and tumorlocation)
排除标准
- •periodical consumption of drugs and pharmaceuticals which influence cortical excitability
- •intraoperative contraindication for required depth of anaesthesia
- •neurological pre-existing illness
- •advanced hepatic insufficiency
研究组 & 干预措施
Brain surgery
Somatosensory evoked potentials in relation to anasthesia (Propofol bolus) induced burst and suppression periods in electroencephalography
干预措施: Propofol (Drug)
Spine surgery
Somatosensory evoked potentials in relation to anasthesia (Propofol bolus) induced burst and suppression periods in electroencephalography
干预措施: Propofol (Drug)
General surgery
Somatosensory evoked potentials in relation to anasthesia (Propofol bolus) induced burst and suppression periods in electroencephalography
干预措施: Propofol (Drug)
结局指标
主要结局
SEP ampiltude in burst-suppression-EEG
时间窗: 2 hours
次要结局
未报告次要终点
研究者
Andrea Szelenyi
Prof. Dr. med. Andrea Szelényi
Heinrich-Heine University, Duesseldorf