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Clinical Trials/NCT05299151
NCT05299151
Completed
Not Applicable

The Effect of Vestibular Rehabilitation on the Kinetic and Kinematic Parameters of Walking in Patients With Multiple Sclerosis

Istanbul Kültür University1 site in 1 country22 target enrollmentJune 1, 2022

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Multiple Sclerosis
Sponsor
Istanbul Kültür University
Enrollment
22
Locations
1
Primary Endpoint
3D Gait Analysis System - pre assesment
Status
Completed
Last Updated
last year

Overview

Brief Summary

In the literature, the results of vestibular rehabilitation treatment applied in patients with Multiple Sclerosis (MS) have been investigated in detail under the headings such as fatigue, physical activity level, and quality of life, and its effects on walking have also been tried to be examined. However, in the studies conducted, gait assessments were made through questionnaires and timed tests, and devices that provide more objective data such as 3-dimensional gait analysis were not used. Again, the effects of vestibular rehabilitation programs on dual-task were not examined in previous studies.

Therefore, the aims of our study are:

  1. To determine the effect of individually designed vestibular rehabilitation exercises on the kinetic and kinematic components of walking;
  2. To determine the effect of vestibular rehabilitation exercises specially designed for the person on gait parameters during cognitive and motor tasks.
Registry
clinicaltrials.gov
Start Date
June 1, 2022
End Date
May 1, 2024
Last Updated
last year
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Sponsor
Istanbul Kültür University
Responsible Party
Principal Investigator
Principal Investigator

Gamze Ertürk

Principal Investigator

Istanbul University - Cerrahpasa (IUC)

Eligibility Criteria

Inclusion Criteria

  • Between aged 25-60 years
  • Diagnosed with MS for at least 5 years
  • Relapsing and progressive MS according to Mc Donald criteria
  • EDSS score of ≤ 3.5 ≤ 6
  • Modified Ashworth Scale \< 3
  • Being eligible to work by a neurologist

Exclusion Criteria

  • Having had an MS-related attack in the 3 months before the study
  • Changes in medications within 6 months prior to the study
  • To have participated in the rehabilitation program within 1 month before the study
  • Serious neurological, cardiac, pulmonary, rheumatological, audiovisual, or orthopedic disorders that limit assessments and/or intervention programs

Outcomes

Primary Outcomes

3D Gait Analysis System - pre assesment

Time Frame: It will be done at the beginning of the study. An analysis session lasts nearly 2 hours per patient. Evaluation of all participants will take approximately 2 months.

Kinetic and kinematic data of gait will be collected in the motion analysis laboratory using 6 infrared digital cameras (Vantage 5.0), 2 synchronized video cameras (Vicon Vue) and 2 force platforms (AMTI).

3D Gait Analysis System - post assesment

Time Frame: It will be done at the end of the study. An analysis session lasting nearly 2 hours per patient. Evaluation of all participants will take approximately 2 months.

Kinetic and kinematic data of gait will be collected in the motion analysis laboratory using

Secondary Outcomes

  • One Leg Standing Test - pre assesment(It will be done at the beginning of the study. The test lasts nearly 5 minutes.)
  • 2 Minute Walking Test - post assessment(It will be done at the end of the study. The test lasts nearly 5 minutes.)
  • One Leg Standing Test - post assessment(It will be done at the end of the study. The test lasts nearly 5 minutes.)
  • Dizziness Handicap Inventory - post assessment(It will be done at the end of the study. The test lasts nearly 15 minutes.)
  • Dizziness Handicap Inventory - pre assessment(It will be done at the beginning of the study. The test lasts nearly 15 minutes.)
  • 2 Minute Walking Test - pre assessment(It will be done at the beginning of the study. The test lasts nearly 5 minutes.)

Study Sites (1)

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