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Gait Analysis in Multiple Sclerosis Patients

Not Applicable
Completed
Conditions
Vestibular Rehabilitation
3D Gait Analysis
Multiple Sclerosis
Interventions
Other: Standard neurorehabilitation exercises
Other: Vestibular exercises
Registration Number
NCT05299151
Lead Sponsor
Istanbul Kültür University
Brief Summary

In the literature, the results of vestibular rehabilitation treatment applied in patients with Multiple Sclerosis (MS) have been investigated in detail under the headings such as fatigue, physical activity level, and quality of life, and its effects on walking have also been tried to be examined. However, in the studies conducted, gait assessments were made through questionnaires and timed tests, and devices that provide more objective data such as 3-dimensional gait analysis were not used. Again, the effects of vestibular rehabilitation programs on dual-task were not examined in previous studies.

Therefore, the aims of our study are:

1. To determine the effect of individually designed vestibular rehabilitation exercises on the kinetic and kinematic components of walking;

2. To determine the effect of vestibular rehabilitation exercises specially designed for the person on gait parameters during cognitive and motor tasks.

Detailed Description

Not available

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
22
Inclusion Criteria
  • Between aged 25-60 years
  • Diagnosed with MS for at least 5 years
  • Relapsing and progressive MS according to Mc Donald criteria
  • EDSS score of ≤ 3.5 ≤ 6
  • Modified Ashworth Scale < 3
  • Being eligible to work by a neurologist
Exclusion Criteria
  • Having had an MS-related attack in the 3 months before the study
  • Changes in medications within 6 months prior to the study
  • To have participated in the rehabilitation program within 1 month before the study
  • Serious neurological, cardiac, pulmonary, rheumatological, audiovisual, or orthopedic disorders that limit assessments and/or intervention programs

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
Standard Neurorehabilitation GroupStandard neurorehabilitation exercisesA neurorehabilitation program based on stretching, strengthening, posture, mobilization, static and dynamic balance exercises will be applied. Each training session will be 40 minutes in total. Exercise training will be done in the clinical setting 2 days a week for 8 weeks, and they will be asked to do it at home once a week.
Vestibular Rehabilitation GroupVestibular exercisesA vestibular rehabilitation exercise program, which is determined based on the literature and personalized according to the functional disabilities of each patient, will be applied to the participants in the experimental group. An exercise session will be performed for a total of 40 minutes, with each exercise for 1-2 minutes. Exercise training will be applied 2 days a week for 8 weeks and they will be asked to do it at home once a week.
Primary Outcome Measures
NameTimeMethod
3D Gait Analysis System - pre assesmentIt will be done at the beginning of the study. An analysis session lasts nearly 2 hours per patient. Evaluation of all participants will take approximately 2 months.

Kinetic and kinematic data of gait will be collected in the motion analysis laboratory using 6 infrared digital cameras (Vantage 5.0), 2 synchronized video cameras (Vicon Vue) and 2 force platforms (AMTI).

3D Gait Analysis System - post assesmentIt will be done at the end of the study. An analysis session lasting nearly 2 hours per patient. Evaluation of all participants will take approximately 2 months.

Kinetic and kinematic data of gait will be collected in the motion analysis laboratory using

Secondary Outcome Measures
NameTimeMethod
One Leg Standing Test - pre assesmentIt will be done at the beginning of the study. The test lasts nearly 5 minutes.

It will be used to determine the patient's standing balance. The duration of standing on one leg will be recorded with a stopwatch and 3 repetitions will be taken and the most successful score will be used in the analysis.

2 Minute Walking Test - post assessmentIt will be done at the end of the study. The test lasts nearly 5 minutes.

The distance that patients will walk for 2 minutes will be measured and recorded.

One Leg Standing Test - post assessmentIt will be done at the end of the study. The test lasts nearly 5 minutes.

It will be used to determine the patient's standing balance. The duration of standing on one leg will be recorded with a stopwatch and 3 repetitions will be taken and the most successful score will be used in the analysis.

Dizziness Handicap Inventory - post assessmentIt will be done at the end of the study. The test lasts nearly 15 minutes.

The Dizziness Disability Inventory consists of 25 items that determine the aggravating factors of patients' dizziness and balance disorder, as well as emotional and functional outcomes in vestibular system diseases. It includes 9 items that determine emotional and functional status, and seven items that determine physical function.

Dizziness Handicap Inventory - pre assessmentIt will be done at the beginning of the study. The test lasts nearly 15 minutes.

The Dizziness Disability Inventory consists of 25 items that determine the aggravating factors of patients' dizziness and balance disorder, as well as emotional and functional outcomes in vestibular system diseases. It includes 9 items that determine emotional and functional status, and seven items that determine physical function.

2 Minute Walking Test - pre assessmentIt will be done at the beginning of the study. The test lasts nearly 5 minutes.

The distance that patients will walk for 2 minutes will be measured and recorded.

Trial Locations

Locations (1)

Istanbul University - Cerrahpaşa, Vocational School of Health Services

🇹🇷

Istanbul, Turkey

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