Effect of Hyaluronan Enriched Embryo Transfer Media on IVF Outcome
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 580
- 试验地点
- 1
- 主要终点
- Clinical pregnancy rate
研究概览
简要总结
Prospective randomized double blind comparison of hyaluronan enriched embryotransfer media and conventional embryotransfer media in human IVF treatments. Embryos selected for transfer are incubated in a culture media containing high concentration of hyaluronan or low concentration of hyaluronan.
Primary outcome: implantation and pregnancy rates
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 48 Years(Adult)
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •Infertile patients
- •entering in vitro fertilization treatment
- •at least 1 embryo transferred
排除标准
- •IVF treatment with donated oocytes
- •No embryo available for transfer
结局指标
主要结局
Clinical pregnancy rate
时间窗: 5 weeks after embryo transfer
Number of clinical pregnancies (gestational sacs visible by ultrasound examination) divided by the number of embryotransfers
Implantation rate
时间窗: 5 weeks after embryotransfer
Number of embryos implanted (No. of gestational sacs) divided by the number of embryos implanted
次要结局
- Multiple pregnancy rate(5 weeks after embryotransfer)
- Delivery rate(40 weeks after embryo transfer)
研究者
Peter Fancsovits, Ph.D.
Senior Clincial Embryologist
Semmelweis University
