Investigating the Effect of Whole-fruit Coffee Extract on Exercise Performance

Not Applicable

Completed

• Conditions: Caffine and Endurance Performance
• Interventions: Dietary Supplement: CoffeeBerry Supplement; Dietary Supplement: Placebo

• Registration Number: NCT05404841
• Lead Sponsor: University of Exeter

Brief Summary

Caffeine is a widely used efficacious supplement by both the general public, and athletes, with the goal of improving performance. The effects of caffeine alone are well known, but it is not clear whether a multi-ingredient supplement (containing both caffeine and polyphenols) can affect exercise performance.

This study aims to determine if a low dose of caffeine, in the form of a whole-fruit coffee extract also containing polyphenols, can improve exercise performance compared to a placebo condition, with a secondary objective of identifying if this supplement can improve post exercise refuelling (glycogen resynthesis).

Participants will consume either the supplement or a placebo before engaging in an exercise protocol. Muscle biopsies will then be obtained so as to measure subsequent glycogen resynthesis, with multiple blood samples being taken through the day. The following morning another biopsy will be taken before the exercise protocol will be repeated.

This research will inform us of the efficacy of caffeine and polyphenols on improving exercise performance.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2022-01-10
• Study Start: 2022-02-04
• Study First Submitted QC: 2022-06-01
• Study First Posted: 2022-06-03
• Primary Completion: 2023-01-25
• Study Completion: 2023-01-25
• Status Verified: 2023-03
• Last Update Submitted: 2023-03-21
• Last Update Posted: 2023-03-22

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 14

Inclusion Criteria

Not provided

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Exclusion Criteria

Not provided

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Study & Design

• Study Type: INTERVENTIONAL
• Study Design: CROSSOVER

Arm && Interventions

Group	Intervention	Description
CoffeeBerry Supplement	CoffeeBerry Supplement	Caffeine and polyphenol supplement
Placebo	Placebo	Placebo

Primary Outcome Measures

Name	Time	Method
Exercise performance	15 Minitues	Amount of work completed in 15 minutes

Secondary Outcome Measures

Name	Time	Method
Rate of perceived exertion	1 Minitue	Validated Borg scale (6-20 Arbitrary units)
Motivation	1 Minitue	10 cm visual analog scale (Ranging from Not motivated to Extremly motivated)
Glycogen Resynthesis	24 Hours	The diffrence in glycogen within the muscle between two time points
Alertness	1 Minitue	10 cm visual analog scale (Ranging from Not Alert to Extremly Alert)
Urine osmolarity	24 Hours	The hydration status of the individual measured in mOsmo\|/kg
GI comfort	1 Minitue	10 cm visual analog scale (Ranging from No discomfort to Extreme discomfort)

Trial Locations

Locations (2)

Sport & Health Sciences University of Exeter; 🇬🇧 Exeter, Devon, United Kingdom

University of Exeter; 🇬🇧 Exeter, United Kingdom