Psychiatric Disorder and Postoperative Morbidity in Hip and Knee Artroplasty

• Conditions: Focus is on Preoperative Psychiatric Charactarization of Elective Fast-track Hip and Knee Arthroplasty Patients

• Registration Number: NCT02576405
• Lead Sponsor: Rigshospitalet, Denmark

Brief Summary

It has been established that patients with psychiatric disorders tend to do worse in a surgical setting. Some types of surgery with greater impact than others, including orthopedic surgery. In our research group the investigators have shown this to be the case for hip and knee replacements within the mentioned patient category. However, the role of psychiatric disorder and use of different psychopharmacological drugs in relation to perioperative morbidity and mortality have not been thoroughly examined. The objective of this study is to shed light on the issue.

Recent studies have shown that different types of psychiatric disorder influence surgical outcome differently. This emphasizes the need for specific knowledge regarding psychiatric diagnoses preoperatively. In this study around 2000 patients with or without psychiatric disorder of any kind will be studied preoperatively, which according to our previous study will include more than 200 patients receiving psychopharmacological treatment. The specifics that characterize every patient's psychiatric trades will be included in a validated questionnaire constructed for that purpose. The questionnaire is called SCL-92 and has been chosen in collaboration with Professor in Psychiatry, Rigshospitalet Anders Fink-Jensen. Preoperative information regarding their mental condition and medicine will be linked to surgical outcome in order to identify potential hazards in the perioperative period.

Detailed Description

Not available

Study Timeline

• Status Verified: 2015-09
• Study Start: 2015-10
• Study First Submitted: 2015-10-13
• Study First Submitted QC: 2015-10-14
• Last Update Submitted: 2015-10-14
• Study First Posted: 2015-10-15
• Last Update Posted: 2015-10-15
• Primary Completion: 2016-10
• Study Completion: 2017-03

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 2000

Inclusion Criteria

• All patients planned for elective unilateral fast-track hip or knee arthroplasty.
• Age > 18.
• Can understand and read danish.

Exclusion Criteria

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Psychological characterization of hip and knee arthroplasty patients using the validated SCL-92 questionnaire	90 days postoperatively

Secondary Outcome Measures

Name	Time	Method
Length of stay	90 days postoperatively
Readmissions	30 and 90 days postoperatively