Conditional Cash Transfers to Increase Uptake of and Retention of PMTCT Services

Not Applicable

Completed

• Conditions: HIV
• Interventions: Behavioral: Conditional cash transfer

• Registration Number: NCT01838005
• Lead Sponsor: University of North Carolina, Chapel Hill

Brief Summary

The goals of the proposed study are to: 1) test whether small, increasing cash payments to HIV-infected pregnant women, on the condition that they attend scheduled clinic visits and receive proposed services, will increase the proportion of women who receive the most effective antiretroviral regimen they are eligible for by the time of delivery, and 2) elucidate factors that facilitate or inhibit the uptake and adherence to the PMTCT cascade, and to what extent the conditional cash payment program addresses these factors.

This intervention will be implemented and evaluated within our well-established PMTCT program in Kinshasa, Democratic Republic of Congo (DRC),

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2013-03-22
• Study Start: 2013-04
• Study First Submitted QC: 2013-04-22
• Study First Posted: 2013-04-23
• Primary Completion: 2015-04
• Study Completion: 2015-04
• Status Verified: 2017-01
• Last Update Submitted: 2017-04-21
• Last Update Posted: 2017-04-25

Recruitment & Eligibility

• Status: COMPLETED
• Sex: Female
• Target Recruitment: 433

Inclusion Criteria

• Newly diagnosed as HIV-positive
• Pregnant between 28 and 32 weeks of gestation (>27 and <32 completed weeks of pregnancy)
• Intend to stay in Kinshasa through delivery and six weeks postpartum
• Able and willing to participate (provide informed consent)

Exclusion Criteria

• Women will be excluded from the study if they are severely ill and require extended hospitalization or need to be cared for at a referral hospital out of the PMTCT network

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Conditional Cash Transfer	Conditional cash transfer	Financial incentive to attend regular clinic visits and receive PMTCT care

Primary Outcome Measures

Name	Time	Method
proportion of women who were adherent to all conditionalities and received the most effective ARV intervention they were eligible to receive and delivered at an affiliated maternity	6 weeks postpartum	At each monthly visit starting at randomization (28 weeks), participants will be evaluated for the following conditionalities: 1. attended the scheduled visit on time (+/- 5 days); 2. accept HIV status and services proposed to them; 3. return to deliver in the clinic At the end of the follow-up (6 weeks post-partum)the proportion of participants who adhered to all these conditions will be calculated for each study group

Secondary Outcome Measures

Name	Time	Method
Mother to child transmission rate at six weeks and HIV-free survival.	6 weeks post partum	Proportion of HIV-exposed infant who tested positive at 6 week postpartum
Proportion of HIV-exposed infants who at their six week visit received extended Nevirapine (NVP) had a DNA PCR test	6 weeks Postpartum	Proportion of infants born to HIV-infected participants who at 6 weeks postpartum are receiving the extended nevirapine prophylaxis and have been tested for HIV
HIV-free survival at 18 month.	18 months porstpartum	Proportion of children born to HIV+ enrolled mothers who are alive and non infected with HIV

Trial Locations

Locations (1)

Kinshasa School of Public Health; 🇨🇬 Kinshasa, Congo