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Clinical Trials/NCT01838005
NCT01838005
Completed
Not Applicable

Conditional Cash Transfers to Increase Uptake of and Retention of PMTCT Services

University of North Carolina, Chapel Hill1 site in 1 country433 target enrollmentApril 2013
ConditionsHIV

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
HIV
Sponsor
University of North Carolina, Chapel Hill
Enrollment
433
Locations
1
Primary Endpoint
proportion of women who were adherent to all conditionalities and received the most effective ARV intervention they were eligible to receive and delivered at an affiliated maternity
Status
Completed
Last Updated
9 years ago

Overview

Brief Summary

The goals of the proposed study are to: 1) test whether small, increasing cash payments to HIV-infected pregnant women, on the condition that they attend scheduled clinic visits and receive proposed services, will increase the proportion of women who receive the most effective antiretroviral regimen they are eligible for by the time of delivery, and 2) elucidate factors that facilitate or inhibit the uptake and adherence to the PMTCT cascade, and to what extent the conditional cash payment program addresses these factors.

This intervention will be implemented and evaluated within our well-established PMTCT program in Kinshasa, Democratic Republic of Congo (DRC),

Registry
clinicaltrials.gov
Start Date
April 2013
End Date
April 2015
Last Updated
9 years ago
Study Type
Interventional
Study Design
Parallel
Sex
Female

Investigators

Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • Newly diagnosed as HIV-positive
  • Pregnant between 28 and 32 weeks of gestation (\>27 and \<32 completed weeks of pregnancy)
  • Intend to stay in Kinshasa through delivery and six weeks postpartum
  • Able and willing to participate (provide informed consent)

Exclusion Criteria

  • Women will be excluded from the study if they are severely ill and require extended hospitalization or need to be cared for at a referral hospital out of the PMTCT network

Outcomes

Primary Outcomes

proportion of women who were adherent to all conditionalities and received the most effective ARV intervention they were eligible to receive and delivered at an affiliated maternity

Time Frame: 6 weeks postpartum

At each monthly visit starting at randomization (28 weeks), participants will be evaluated for the following conditionalities: 1. attended the scheduled visit on time (+/- 5 days) 2. accept HIV status and services proposed to them 3. return to deliver in the clinic At the end of the follow-up (6 weeks post-partum)the proportion of participants who adhered to all these conditions will be calculated for each study group

Secondary Outcomes

  • Mother to child transmission rate at six weeks and HIV-free survival.(6 weeks post partum)
  • Proportion of HIV-exposed infants who at their six week visit received extended Nevirapine (NVP) had a DNA PCR test(6 weeks Postpartum)
  • HIV-free survival at 18 month.(18 months porstpartum)

Study Sites (1)

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