Study for biomarkers and molecular pathophysiology of depression diversity
- Conditions
- Major depressive disorder
- Registration Number
- JPRN-UMIN000007825
- Lead Sponsor
- Gunma University Graduate School of Medicine
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 80
Not provided
This study excludes major depressive patients and age- and gender-matched healthy controls, in accordance with following exclusion criteria. 1) The subjects with contraindication for MRI, i.e., heart pacer user 2) The subjects with significant physical illness 3) The pregnant or lactating women 4) The Patents during involuntary admission 5) The Patents during emergency admission 6) The patients, whom medical doctor exclude as impropriety 7) The healthy controls, who has a the first-degree relatives with psychiatric disorders 8) The patients with below 23 points of MMSE
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Assessments by Near Infra- Red Spectoroscopy, 123I-IMP-SPECT, 3T-Magnetic Resonance Image (MRI), gene and blood sampling to compare among young-onset (onset below 40 aged), middle- or senile-onset (onset above 40 aged) depressive patient and healthy control groups.
- Secondary Outcome Measures
Name Time Method Assessment by prognosis after treatment, and atherosclerotic factors.