The Effects of Barberry Juice Consumption on Glycaemic Control, Lipid Profile, Blood Pressure and Oxidative Stress in Patients With Type 2 Diabetes: A Randomized Clinical Trial
试验速览
- 阶段
- 4 期
- 状态
- 已完成
- 发起方
- 入组人数
- 46
- 主要终点
- fasting blood glucose
研究概览
简要总结
The aim of this study was to investigate the effect of barberry juice (BJ) as a natural antioxidant, on cardiovascular risk factors in patients with type 2 diabetes (T2DM). In a randomized clinical trial study, 46 T2DM patients, 30-70 years old recruited from "Diabetes Association of Iran-Babul ". Patients were randomly allocated to either the BJ group (n=23) who consumed 200 ml of BJ daily for eight weeks, or the control group (n=23) with no intervention. At the baseline and the end of 8-week intervention, blood pressure and biochemical markers were conducted.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Supportive Care
- 盲法
- None
入排标准
- 年龄范围
- 30 Years 至 70 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Fasting blood glucose>100 mg/dL (5.6 mmol /L)
- •Systolic blood pressure>130 mmHg or diastolic blood pressure>85mmHg
- •Triglycerides> 150 mg/dL (1.7 mmol/L)
排除标准
- •taking insulin
- •using antioxidant supplements
研究组 & 干预措施
Intervention group
patients in this group were received 200 ml/d barberry juice for tow month
干预措施: barberry juice (Other)
control group
patients in this group received no intervention
结局指标
主要结局
fasting blood glucose
时间窗: 8 weeks
total cholesterol
时间窗: 8 weeks
次要结局
- HbA1c(8 weeks)
- Diastolic BP(8 weeks)
- HDL- cholesterol(8 weeks)
- LDL- cholesterol(8 weeks)
- Triglyceride(8 weeks)
- Systolic BP(8 weeks)
研究者
Dr Azita Hekmatdoost
National Nutrition and Food Technology Research Institute
National Nutrition and Food Technology Institute