A Prospective Study on The"Management of Hypertension in Young and Middle-aged Subjects in Enterprises Setting"
试验速览
- 阶段
- 不适用
- 状态
- 暂停
- 发起方
- 入组人数
- 2,000
- 试验地点
- 1
- 主要终点
- Diagnostic classification in hypertension
研究概览
简要总结
In recent years, with the investment from government in the health management of the elderly, community management of hypertension in the elderly has made great progress in management rate and standardized management, but the management of young and middle-aged patients with hypertension is still blank.
Workplace pressure measurement may be more suitable for most of the young and middle-aged patients to find high blood pressure and monitor blood pressure changes in time.
However, there is not much research on workplace pressure measurement. Whether blood pressure measurement in the workplace can reduce the white coat effect, and how it relates to home blood pressure and ambulatory blood pressure is still unclear.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 65 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Male and female sex, aged 18-65 years
- •Three different daytime workplace blood pressure measurements meet the limits: systolic blood pressure ≥ 120 mmHg, or diastolic blood pressure ≥80 mmHg
- •Hypertensive patients who are taking antihypertensive drugs
- •Willing to provide information about disease history and lifestyle
- •Willing to receive follow-up for up to 2-3 years
- •Sign the informed consent
排除标准
- •Having the onset of cardiovascular and cerebrovascular diseases such as stroke, myocardial infarction or heart failure within 6 months
- •Having a history of atrial fibrillation or frequent arrhythmia
- •Complicating other diseases that are not suitable for the trial, such as thyroid disease with active medication, acute infectious diseases, chronic mental illness, and tumors
- •The subject is participating in other clinical studies.
结局指标
主要结局
Diagnostic classification in hypertension
时间窗: 2 years
Differences in diagnostic classification between workplace blood pressure and daytime ambulatory blood pressure in the classification of hypertension (masked hypertension or white coat hypertension)
次要结局
- Change in different blood pressure measurement(2 years)
- The distribution of heart rate in young and middle-aged subjects(2 years)
- Progression of target organ damage(2 years)
- The development of with-coat hypertension(2 years)
- The proportion of masked hypertension in patients with normal high blood pressure(2 years)
研究者
Yan Li
Professor of Cardiovascular Medicine
Shanghai Institute of Hypertension