Abnormal Uterine Bleeding and the Histopathological spectrum : An observational study
- Conditions
- Abnormal uterine and vaginal bleeding, unspecified,
- Registration Number
- CTRI/2023/03/050523
- Lead Sponsor
- self YogeswariS
- Brief Summary
Abnormal Uterine Bleeding is the most common presenting complaint among women of
all age group visiting Gynecology . One third of patients attending gynaecology OPD
present with complaints of abnormal uterine bleeding(1). AUB is charecterised by any
deviation form the normal pattern/frequency, duration and severity of normal menstrual
flow.Recently, the International Federation of Gynecology and Obstetrics
working group on menstrual disorder has developed a
classification system (PALM-COEIN) for causes of the
AUB in non-gravid women of reproductive age. There
are nine main categories, which are arranged according
to the acronym PALM-COEIN: Polyp; adenomyosis;
leiomyoma; malignancy and hyperplasia; coagulopathy;
ovulatory dysfunction; endometritis; iatrogenic; and not
yet classified [2].Although radiological examination is the first mode of diagnosis in most
cases, Histopathological evaluation is the most relied method for diagnosis and planning
further management.The various mode of obtaining Endometrial samples like – D and C,
Endocell, Mannual vaccum aspiration have made the diagnosis of AUB much easier.
Endometrial biopsy and curettage are chief sampling methods [3].The cause of AUB may
widely vary from a simple polyp to malignancy. AUB in perimenopausal and
postmenopausal patients warrants thorough evaluation because AUB is the only clinical
symptom of endometrial carcinoma in most patients.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Not Yet Recruiting
- Sex
- Female
- Target Recruitment
- 405
All Women between age 19-70 Presenting to gynecology opd with complaints of Abnormal uterine bleeding.
Not provided
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To study the various Clinico- pathological Pattern 2 weeks and 4 weeks in women with Abnormal Uterine Bleeding from different age groups 2 weeks and 4 weeks
- Secondary Outcome Measures
Name Time Method a. To compare the different diagnostic modalities used to obtain Endometrial tissue Sampling.
Trial Locations
- Locations (1)
KMC manipal
🇮🇳Udupi, KARNATAKA, India
KMC manipal🇮🇳Udupi, KARNATAKA, IndiaYogeswariPrincipal investigator9789675787yogi98.sf@gmail.com
