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Study to assess whether preoperative chemotherapy in Periampullary carcinoma increases survival

Phase 3
Conditions
Health Condition 1: C248- Malignant neoplasm of overlappingsites of biliary tract
Registration Number
CTRI/2024/05/067431
Lead Sponsor
AIIMS PATNA
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Open to Recruitment
Sex
Not specified
Target Recruitment
0
Inclusion Criteria

1.Periampullary carcinoma which are resectable on imaging studies

2.ECOG grade 0-II

3.Biopsy proven periampullary carcinoma

Exclusion Criteria

1.Borderline resectable and locally advanced disease

2.Contraindication to use of chemotherapy

3.Ca head of pancreas

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
1.Local recurrence in the two groups <br/ ><br>2.Distant metastasis in the two groupsTimepoint: Disease free survival at 2 years <br/ ><br>
Secondary Outcome Measures
NameTimeMethod
3.Overall survival in the two groups <br/ ><br>4.Resection rate <br/ ><br>5.R0 resection <br/ ><br>6.Adverse events related to chemotherapy <br/ ><br>Timepoint: Overall survival at 5 years
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