Pilot Study of Maintenance Therapy With Intravenous AMANTADINE
- Registration Number
- NCT01190553
- Lead Sponsor
- Rabin Medical Center
- Brief Summary
This is a pilot study for Maintenance Intravenous Treatment with AMANTADINE in patient with PARKINSON'S Disease who are not well balanced with medical treatment.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- UNKNOWN
- Sex
- All
- Target Recruitment
- 20
Inclusion Criteria
- Patients with idiopathic Parkinson disease
- Age<80
- Patients with no motor improvement under optimal treatment with anti parkinson medications
- Patients with moderate to severe dyskinesias
- Patients with PD with side effects who can not tolerate anti parkinson medications
Exclusion Criteria
- Age>80
- Patients with Parkinson syndromes, vascular parkinsonism or drug-induced parkinsonism
- Patients with PD who developed adverse reactions to oral amantadine
- Contraindication of amantadine treatment
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- SINGLE_GROUP
- Arm && Interventions
Group Intervention Description Treatment Amantadine IV amantadine treatment
- Primary Outcome Measures
Name Time Method Improvement of UPDRS scores after 6 months of treatment 6 months Improvement of dyskinesias score. 6 months
- Secondary Outcome Measures
Name Time Method