Prevalence of Osteoporosis in Sickle Cell Disease
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 142
- 试验地点
- 1
- 主要终点
- Bone mineral density
研究概览
简要总结
Sickle cell disease is the most common single-gene disease in the world. Its prevalence is increasing in France, with patients' life expectancy increasing into developed countries. It mainly affects populations originating from sub-Saharan Africa. Among the chronic bone complications associated with sickle cell disease, osteoporosis has previously been highlighted but remains a poorly known complication in this very particular context. A dedicated evaluation of osteoporosis and associated risk factors in sickle cell disease patients living in France may enable better bone management of these patients in the future, as this problem, specific to their disease, is likely to become more frequent as their life expectancy increases.
This is a prospective interventional and monocentric study whose objective is to describe the prevalence of osteoporosis in black patients with sickle cell disease in France
研究设计
- 研究类型
- Observational
- 观察模型
- Case Only
- 时间视角
- Prospective
入排标准
- 年龄范围
- 20 Years 至 40 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Black-skinned men and women
- •Aged 20 to 40 years old
- •Sickle cell patients
- •Non-opposition to participate in the study
排除标准
- •Refusal to participate in the study
- •Hemoglobinopathy other than sickle cell disease
- •Severe or End Stage Renal Failure
- •Long-term corticosteroid therapy (>3 months)
- •History of solid cancer or malignant haemopathy
- •History of organ transplantation
- •Pregnant or breastfeeding woman
- •Psychiatric pathology seriously impeding understanding
- •Difficulty understanding oral French
结局指标
主要结局
Bone mineral density
时间窗: Day 1
Bone mineral density is measured by systematic bone densitometry at 3 sites: lumbar spine, femoral neck and total hip. These data will be collected in the patient's medical record
次要结局
未报告次要终点