the Impact of Nutritional Status on Clinical Outcome of Children Admitted in PICU OF Assuit Children University Hospital
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Nutritional Disorder
- Sponsor
- Assiut University
- Enrollment
- 80
- Primary Endpoint
- the correlation between nutritional status of children admitted in PICU and outcomes
- Last Updated
- 6 years ago
Overview
Brief Summary
Malnutrition is believed to be associated with clinical outcomes in ill patients and several studies have shown that nutrition status play a major role in disease prognosis in adults .
Different authors have described an increase in morbidity and mortality attributable to malnutrition, as it lead to state of partial immunosuppression, delay wound healing ,causes muscular atrophy and increase length of stay.
Detailed Description
Several studies have investigated the predictive role of an extremely low body weight on disease prognosis and outcomes among general and critically ill children .They enrolled all patients consecutively admitted to pediatric intensive care unit PICU) , therefore , being underweight may have resulted from endocrine diseases, genetic syndromes or other systemic underlying illnesses . The impact of low body weight on outcomes of acutely critically ill but previously healthy children is still unknown. Many studies evaluate the clinical status and outcome by pediatric index of mortality (PIM2) as a popular and reliable predictive score . In this study, we will investigate the impact of being underweight or proper weight on mortality and morbidity among acute critically ill children with no genetic, endocrine, or chronic systemic illness at PICU admission
Investigators
Hager Adel Ali
principal investigator
Assiut University
Eligibility Criteria
Inclusion Criteria
- •All children admitted to PICU with nutritional disorders
- •Children with acute diseases and anthropometric measurements taken within first 24hours
Exclusion Criteria
- •1-children with underlying chronic diseases (eg cerebral palsy ,type 1 or 2 diabetes , epilepsy, metabolic diseases, inflammatory bowel disease , liver cirrhosis , immunodeficiency , autoimmune disordes , malignancy , chronic kidney disease) and postoperative patients.
Outcomes
Primary Outcomes
the correlation between nutritional status of children admitted in PICU and outcomes
Time Frame: 2 years
nutritional status measured by weight in kilograms and height in meters will be combined to report BMI for Z scoreand outcomes measured by pediatric index of mortality2 (PIM2)