A preventive effect of pancreatic duct stenting to decrease the rate of pancreatic fistula after pancreaticojejunostomy following pancreatoduodenectomy - A preventive effect of pancreatic duct stenting to decrease the rate of pancreatic fistula after pancreaticojejunostomy

The rate of clinically relevant POPF was significantly lower in the stented group than in the non-stented group: three of 47 (6 per cent) versus ten of 46 (22 per cent) (P = 0.040). Among patients with a dilated duct, rates of POPF were similar in both groups. Among patients with a non-dilated duct, clinically relevant POPF was significantly less common in the stented group than the non-stented group: two of 21 (10 per cent) versus eight of 20 (40 per cent) (P = 0.033). Univariable analysis identified body mass index (BMI), pancreatic cancer, pancreatic texture, pancreatic duct size and duct stenting as risk factors related to clinically relevant POPF. Multivariable analysis taking these five factors into account identified high BMI (risk ratio (RR) 11.4; P = 0.009), non-dilated duct (RR 5.33; P = 0.047) and no stent (RR 10.4; P = 0.004) as significant risk factors.