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Clinical Trials/NCT06274918
NCT06274918
Completed
Not Applicable

Reducing Intraoperative ESKAPE (Enterococcus, S. Aureus, Klebsiella, Acinetobacter, Pseudomonas, and Enterobacter Spp.) Transmission Via Use of an Evidence-Based, Hand Hygiene Program Optimized by OR PathTrac

University of Iowa1 site in 1 country39 target enrollmentFebruary 1, 2023

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Surgical Procedure, Unspecified
Sponsor
University of Iowa
Enrollment
39
Locations
1
Primary Endpoint
ESKAPE transmission events with and without the body worn device
Status
Completed
Last Updated
11 months ago

Overview

Brief Summary

This study is designed to examine the impact of a personalized, body worn alcohol dispenser on the epidemiology of ESKAPE transmission in the anesthesia work area for patients undergoing surgery requiring general anesthesia.

Detailed Description

A solid body of published and preliminary evidence leveraging systematic phenotypic and whole cell genome analysis and innovative surveillance technology has provided great insight into the epidemiology of perioperative bacterial transmission and healthcare-associated infection (HAI) development. This work has led us to three primary assertions that serve as the foundation of our scientific premise: 1) Further progress towards HAI prevention is needed, 2) Prevention of perioperative ESKAPE transmission is an important improvement target, and 3) An evidence-based, multi-faceted program can reduce perioperative ESKAPE transmission. Further work to generate intraoperative hand hygiene improvement is indicated. We hypothesize that the proposed program will generate sustained reductions in OR ESKAPE exposure and S. aureus transmission that will lead to sustained reductions in perioperative HAIs.

Registry
clinicaltrials.gov
Start Date
February 1, 2023
End Date
December 12, 2024
Last Updated
11 months ago
Study Type
Observational
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Andrew Pugely

Principle Investigator

University of Iowa

Eligibility Criteria

Inclusion Criteria

  • Adult patients undergoing surgery requiring general anesthesia and peripheral IV and/or central line placement.

Exclusion Criteria

  • Pediatric patient, not requiring general anesthesia and/or IV/central line placement.

Outcomes

Primary Outcomes

ESKAPE transmission events with and without the body worn device

Time Frame: Up to 96 hours from the surgial procedure

Reduce the number of Enterococcus, Staphylococcus aureus, Pseudomonas, and other gram-negative (i.e., Klebsiella, Acinetobacter, Pseudomonas, and Enterobacter spp.) transmission events

Secondary Outcomes

  • 90-Day Healthcare-Associated Infections(90 days following surgery)
  • The epidemiology of ESKAPE transmission events(Up to 90 days from surgery)

Study Sites (1)

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