Assessment of Nutritional Status and Role of Insulin-like Growth Factor-1 in Children

Completed

• Conditions: Thalassemia

• Registration Number: NCT05529550
• Lead Sponsor: Menoufia University

Brief Summary

Many studies done on children with thalassemia have shown a variable prevalence of defective IGF-I concentrations have been shown to be low in the majority of children, with or without GH deficiency. The Aim of this study to assess nutritional status and role of Insulin-like growth factor 1 (IGF-1) and its associating factors in children with thalassemia major

Detailed Description

Not available

Study Timeline

• Study Start: 2020-10-01
• Primary Completion: 2021-11-01
• Study Completion: 2021-12-01
• Status Verified: 2022-09
• Study First Submitted: 2022-09-02
• Study First Submitted QC: 2022-09-02
• Last Update Submitted: 2022-09-02
• Study First Posted: 2022-09-07
• Last Update Posted: 2022-09-07

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 102

Inclusion Criteria

• Children in the age group of 2-18 years with confirmed diagnosis of Beta thalassemia major.

Exclusion Criteria

• Children with other chronic diseases (cardiac, renal, vascular)
• Children with malignancy

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
IGF-1	at the time of recruitment	insulin-like growth factor-1 which measured by enzyme linked immunosorbent assay (ELISA).

Trial Locations

Locations (1)

Samar Abd El-Hameed; 🇪🇬 Shibīn Al Kawm, Egypt