Does previous pregnancy loss increase the risk for gestational diabetes?
- Conditions
- Gestational DiabetesPregnancy lossReproductive health and childbirthMetabolic and Endocrine - DiabetesReproductive Health and Childbirth - Antenatal careReproductive Health and Childbirth - Fetal medicine and complications of pregnancy
- Registration Number
- ACTRN12624000956505
- Lead Sponsor
- Sutherland Hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot yet recruiting
- Sex
- Female
- Target Recruitment
- 1000
1) The exposure group consists of pregnant women with gestational diabetes who attended the antenatal Endocrine clinic at Sutherland Hospital during their pregnancy between 2016 and 2018.
2) The control group consists of pregnant women without a diagnosis of gestational diabetes, matched by age, BMI, and ethnicity, who also attended the antenatal Endocrine clinic at Sutherland Hospital during their pregnancy between 2016 and 2018.
3) Data for 150 participants collected in year 2022 as part of the study: To determine an association between metformin use in gestational diabetes mellitus and vitamin B12 deficiency (trial id: ACTRN12620000397910) will also be included in this study.
Women with Type 1 and 2 pre-gestational diabetes as well as women with BMI exceeding 35 kg/m2 will be excluded from the analysis, as their care was transferred to the tertiary referral centre.
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The study primary outcome is frequency of pregnancy loss in women with gestational diabetes as determined from medical records. [ The study primary timepoint is the timing of delivery ]
- Secondary Outcome Measures
Name Time Method Diagnosis of gestational diabetes in women with and without history of pregnancy loss, determined from medical records.[ The timepoint of gestational diabetes diagnosis. ]