Efficacy of Seprafilm for prevention of postoperative adhesions in repeat hepatectomy of recurrent liver tumors. Prospctive Randomized Controlled Trial

Phase 3

• Conditions: hepatocellular carcinoma or colorectal liver metastases

• Registration Number: JPRN-UMIN000014460
• Lead Sponsor: Department of Digestive Surgery, Nihon University School of Medicine

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2014-07-11
• Study Completion: 2019-03-31
• Last Update Posted: 17 October 2023

Recruitment & Eligibility

• Status: Complete: follow-up complete
• Sex: All
• Target Recruitment: 1000

Inclusion Criteria

Not provided

Exclusion Criteria

1) Severe comorbidity 2) Severe infectious disease 3) Pleural effusion, ascites fluid and the pericardial fluid needing treatment 4) Patients with other primary malignancies. 5) A past history of drug allergy (needs continuation therapy) 6) Chronic systemic treatment of corticosteroid 7) Bleeding tendency, coagulation disorder, abnormality of coagulation factor, or administered anticoagulant 8) Patients infected with human immunodeficiency virus (HIV)/acquired immunodeficiency syndrome (AIDS). 9) Patients during pregnancy, breast- feeding, or at risk of becoming pregnant. 10) Psychological disorder 11) Considered not appropriate for surgery 12) Patients considered inappropriate by the study investigator

Study & Design

• Study Type: Interventional
• Study Design: Not specified