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Clinical Trials/NCT06050135
NCT06050135
Active, Not Recruiting
N/A

Roadmap to Parenthood: Testing the Efficacy of a Decision Aid and Planning Tool for Family Building After Cancer

Stanford University1 site in 1 country260 target enrollmentMay 20, 2024

Overview

Phase
N/A
Intervention
Roadmap to Parenthood
Conditions
Quality of Life
Sponsor
Stanford University
Enrollment
260
Locations
1
Primary Endpoint
Decision Conflict Scale
Status
Active, Not Recruiting
Last Updated
2 months ago

Overview

Brief Summary

This study will test a decision support intervention that consists of a web-based 'decision aid and planning tool' for family building after cancer in a randomized controlled trial.

Registry
clinicaltrials.gov
Start Date
May 20, 2024
End Date
February 10, 2027
Last Updated
2 months ago
Study Type
Interventional
Study Design
Parallel
Sex
Female

Investigators

Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • Assigned female at birth
  • Aged 18 to 45 years old
  • Understands verbal and written English
  • History of a cancer diagnosis.
  • Completed cancer treatment(s) with known or uncertain gonadotoxic effects (e.g., systemic chemotherapy, surgery or radiation affecting reproductive organs or hormone regulation, stem cell or bone marrow transplant, and/or immunotherapy)
  • Interested in having a future child (or more children) or uncertain about family building plans
  • Access to the Internet and use of a computer, tablet, or smartphone
  • Ability to understand and the willingness to personally sign the written IRB-approved informed consent document

Exclusion Criteria

  • Currently undergoing cancer treatment excluding long term adjuvant or maintenance therapies, such as tamoxifen
  • Significant physical or mental disability that prevents completion of study activities

Arms & Interventions

Web-based decision support (Roadmap to Parenthood)

Patients will receive access to the Roadmap to Parenthood tool (website). The goal of the Roadmap tool is to encourage young adult females (YA-Fs) to be informed about family-building options, set realistic expectations about potential difficulties, and plan ahead to avoid or mitigate barriers, while also inspiring hope and confidence that parenthood may be achieved, despite their cancer histories.

Intervention: Roadmap to Parenthood

Informational booklet

Patients will receive the web-based Livestrong 'Planning for Life After Cancer: A Guide to Survivorship for Teens and Young Adults' informational booklet, covering many topics (e.g., physical symptoms, emotional concerns, day-to-day needs).

Intervention: Informational Booklet

Outcomes

Primary Outcomes

Decision Conflict Scale

Time Frame: 12 months

Decisional Conflict Scale is a validated survey that assesses personal uncertainty in making healthcare decisions; modifiable factors contributing to uncertainty; and the quality of the decision made. The survey has 16 questions, with responses on a 5 point scale ranging from "strongly agree" (1) to "strongly disagree" (5). Total scores range from 16 to 80, with higher scores indicating greater uncertainty (worse outcome)

Secondary Outcomes

  • Patient-Reported Outcomes Measure-29 (PROMIS-29) Quality of Life(12 months)
  • Planning Behaviors for Future Family Building(12 months)

Study Sites (1)

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