Comparative Evaluation of the Effect of Oral Premedication with a Single Dose of Ketorolac, Dexamethasone and Tramadol Hydrochloride on the Incidence and Intensity of Post Operative Endodontic Pain: A Double Blinded Randomized Controlled Clinical Trial
试验速览
- 阶段
- 4 期
- 状态
- 尚未招募
- 入组人数
- 120
- 试验地点
- 1
- 主要终点
- Incidence & intensity of post endodontic pain.
研究概览
简要总结
After the clinical examination and diagnosis of symptomatic irreversible pulpitis patients will be divided into four groups by random sequencing. Procedure will be explained to the patients and informed consent will be taken from the patients. Patients will be given drugs by the operator unaware of the drug coding and patient unaware of the drug composition 1 hour prior to the treatment. Single visit root canal treatment will be performed by the operator and pain history on HP-VAS scale along wiith rescue drug requirement and intake at 4 hours, 8 hours, 12 hours,24 hours,48 hours interval following the first visit.
研究设计
- 研究类型
- Interventional
- 分配方式
- Computer generated randomization
- 盲法
- Participant and Investigator Blinded
入排标准
- 年龄范围
- 25.00 Year(s) 至 55.00 Year(s)(—)
- 性别
- All
入选标准
- •1-Mature permanent mandibular posteriors with symptomatic irreversible pulpitis.
- •2-Teeth having sufficient tooth structure for adequate isolation.
- •3-No history of previous endodontic therapy.
- •4-No history of trauma to the involved tooth.
排除标准
- ••Patients who have a positive history of analgesic intake within past 3 days.
- ••Patients with periapical lesion.
- ••Patients who have a positive history of antibiotics intake in the last month.
- ••Patients with known history of allergy to the drugs in study.
- ••Diabetic, immunocompromised patients, pregnant, lactating females.
- ••Calcified roots.
结局指标
主要结局
Incidence & intensity of post endodontic pain.
时间窗: 4 hours,8 hours,12hours,24 hours, 48 hours
次要结局
- Need & amount of rescue medication for the control of post operative pain(4 hours,8 hours,12hours,24 hours, 48 hours)
