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临床试验/CTRI/2023/08/056259
CTRI/2023/08/056259尚未招募4 期

Comparative Evaluation of the Effect of Oral Premedication with a Single Dose of Ketorolac, Dexamethasone and Tramadol Hydrochloride on the Incidence and Intensity of Post Operative Endodontic Pain: A Double Blinded Randomized Controlled Clinical Trial

SGT UNIVERSITY1 个研究点 分布在 1 个国家目标入组 120 人开始时间: 2023年8月19日最近更新:

试验速览

阶段
4 期
状态
尚未招募
入组人数
120
试验地点
1
主要终点
Incidence & intensity of post endodontic pain.

研究概览

简要总结

After the clinical examination and diagnosis of symptomatic irreversible pulpitis patients will be divided into four groups by random sequencing. Procedure will be explained to the patients and informed consent will be taken from the patients. Patients will be given drugs by the operator unaware of the drug coding and patient unaware of the drug composition 1 hour prior to the treatment. Single visit root canal treatment will be performed by the operator and pain history on HP-VAS scale along wiith rescue drug requirement and intake at  4 hours, 8 hours, 12 hours,24 hours,48 hours interval following the first visit.

研究设计

研究类型
Interventional
分配方式
Computer generated randomization
盲法
Participant and Investigator Blinded

入排标准

年龄范围
25.00 Year(s) 至 55.00 Year(s)(—)
性别
All

入选标准

  • 1-Mature permanent mandibular posteriors with symptomatic irreversible pulpitis.
  • 2-Teeth having sufficient tooth structure for adequate isolation.
  • 3-No history of previous endodontic therapy.
  • 4-No history of trauma to the involved tooth.

排除标准

  • •Patients who have a positive history of analgesic intake within past 3 days.
  • •Patients with periapical lesion.
  • •Patients who have a positive history of antibiotics intake in the last month.
  • •Patients with known history of allergy to the drugs in study.
  • •Diabetic, immunocompromised patients, pregnant, lactating females.
  • •Calcified roots.

结局指标

主要结局

Incidence & intensity of post endodontic pain.

时间窗: 4 hours,8 hours,12hours,24 hours, 48 hours

次要结局

  • Need & amount of rescue medication for the control of post operative pain(4 hours,8 hours,12hours,24 hours, 48 hours)

研究者

申办方类型
Research institution and hospital

研究点 (1)

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