Efficacy of ultrasound guided radiofrequency ablation of breast carcinomas <= 2cm

Phase 2

Completed

• Conditions: breast cancer; breast carcinoma; 10006291; 10006295

• Registration Number: NL-OMON38082
• Lead Sponsor: niversitair Medisch Centrum Utrecht

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 6 May 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 24

Inclusion Criteria

Women >18 years diagnosed with a cT1 breast carcinoma
Signed informed consent
On large core needle biopsy determined tumorcharacteristics (i.e.estrogen and Progesterone receptor status, Bloom and Richardson, Mitose Activity Index and Her2Neu expression)

Exclusion Criteria

pregnancy
unknown tumorcharacteristics (i.e. estrogen and progestorone receptor status, B&R, MAI and Her2Neu expression)
In situ carcinoma

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>1) Histopathological tumor vitality after RFA using NADH staining<br /><br><br /><br>2) Margin of tumor free tissue ablated around the tumor</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>Not applicable</p><br>