Effect of a single session of physical exercise on blood markers in adult individuals with incomplete spinal cord injury

Not Applicable

• Conditions: Spinal cord injury; P11.5

• Registration Number: RBR-5chrq5
• Lead Sponsor: Centro Universitário Metodista-IPA

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2019-04-22
• Last Update Posted: 29 May 2023

Recruitment & Eligibility

• Status: Data analysis completed
• Sex: Not specified
• Target Recruitment: Not specified

Inclusion Criteria

For both groups, individuals with incomplete traumatic LM; aged between seventeen and fifty-five years old; of both genders and diagnosed for at least 6 months and at most 5 years of injury, will be included. For the trained groups, the subjects should be submitted to an intervention program (neurofunctional rehabilitation) for at least 6 months. For untrained groups, individuals should be performing only conventional physiotherapy.

Exclusion Criteria

As exclusion criteria, for both groups, all those with contraindications to weight support, such as individuals with hip fracture or lower limb or who present scabs, are included. Also, patients who present with unstable angina or other decompensated heart disease; chronic obstructive pulmonary disease; neurological diseases such as Parkinson's; stroke; who exhibit symptomatic drop in blood pressure when upright; who use medications with HDAC inhibitors valproic acid) and are undergoing active inflammation / infection.

Study & Design

• Study Type: Intervention
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Increase of 50% on levels of histone acetylation and reduction of inflammatory markers and muscle injury after soil and treadmill intervention.

Secondary Outcome Measures

Name	Time	Method
Increase of 50% on electromyographic activity of the quadriceps muscle with the intervention.