Effect of a single session of gait training with body weight support on epigenetic parameters, brain derived neurotrophic factor levels and injury markers and peripheral blood muscle repair in adult individuals with incomplete spinal cord injury

Centro Universitário Metodista-IPA0 个研究点开始时间: 2019年4月22日最近更新: 2023年5月29日

适应症

试验速览

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•For both groups, individuals with incomplete traumatic LM; aged between seventeen and fifty-five years old; of both genders and diagnosed for at least 6 months and at most 5 years of injury, will be included. For the trained groups, the subjects should be submitted to an intervention program (neurofunctional rehabilitation) for at least 6 months. For untrained groups, individuals should be performing only conventional physiotherapy.

•As exclusion criteria, for both groups, all those with contraindications to weight support, such as individuals with hip fracture or lower limb or who present scabs, are included. Also, patients who present with unstable angina or other decompensated heart disease; chronic obstructive pulmonary disease; neurological diseases such as Parkinson's; stroke; who exhibit symptomatic drop in blood pressure when upright; who use medications with HDAC inhibitors valproic acid) and are undergoing active inflammation / infection.

发起方

Centro Universitário Metodista-IPA