Near-focus Versus Normal-focus Narrow Band Imaging Colonoscopy in Diagnosis of Colorectal Polyps Based on Combined NICE and WASP Classification: a Randomized Controlled Trial
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Colorectal Polyp
- Sponsor
- Prince of Songkla University
- Enrollment
- 118
- Locations
- 1
- Primary Endpoint
- Rate of accurate diagnosis of sessile serrated polyps/adenoma by the Endoscopists in the two groups.
- Status
- Completed
- Last Updated
- 4 years ago
Overview
Brief Summary
Optical diagnosis of colorectal polyps is a promising tool to avoid risks of unnecessary polypectomies and to save costs of tissue pathology. NICE (NBI International Colorectal Endoscopic) and WASP (Workgroup on Serrated Polyps and Polyposis) classification were developed for diagnosis of adenomatous and sessile serrated polyps, respectively.
Detailed Description
Near-focus (NF) narrow-band imaging (NBI) is an image-magnifying technology which enables optical magnification of up to 65x in near focus (NF) compared with 52x in normal standard focus (SF) with the simple push of a button of the endoscope to be interchangeable between NF and SF. There were few studies comparing diagnostic accuracy between NF and SF in the diagnosis of colorectal polyps. So, our aim of the current study is to compare accuracy of NF NBI compared with SF NBI in the optical diagnosis of neoplastic and non-neoplastic polyp and the accuracy of NF NBI versus SF NBI in distinguishing serrated adenoma from hyperplastic polyp in sessile lesions using histologic evaluation as the gold standard.
Investigators
Nisa Netinatsunton
Principal Investigation
Prince of Songkla University
Eligibility Criteria
Inclusion Criteria
- •Patients who were scheduled for colonoscopy at NKC institute
Exclusion Criteria
- •Inflammatory bowel disease
- •Polyposis syndrome
- •Colorectal cancer
- •Active gastrointestinal bleeding
- •Pregnant woman
- •Inadequate bowel preparation
- •Contraindication for polyps removal
Outcomes
Primary Outcomes
Rate of accurate diagnosis of sessile serrated polyps/adenoma by the Endoscopists in the two groups.
Time Frame: At the time of procedure
Measure of the percentage od accurate predictions by the endoscopists in the differentiation of sessile serrated polyps/adenoma from hyperplastic polyps, using the high definition NBI colonoscopy with and without near focus features.
Rate of accurate polyp histology predictions by the Endoscopists in the two groups.
Time Frame: At the time of procedure
Measure of the percentage of accurate predictions by the endoscopists in the differentiation of neoplastic from non neoplastic colorectal lesions, using the high definition NBI colonoscopy with and without near focus features
Secondary Outcomes
- The adenoma detection rate(At the time of procedure)
- The polyp detection rate(At the time of procedure)
- Diagnostic Characteristics(At the time of procedure)