Prevalence Of Prediabetes And Diabetes In First Degree Relatives Of Diabetes Patients
Not Applicable
- Registration Number
- CTRI/2021/09/036369
- Lead Sponsor
- Maulana Azad Medical College
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
1.Adults who are the first degree relatives of type 2 diabetes mellitus patients
Exclusion Criteria
1.Patients with active malignancy
2.People living with HIV
3.Patients on immunosuppressive agents
4.Patients with chronic comorbid conditions such as Chronic Liver Disease, Chronic Kidney Disease, Coronary Artery Disease
5.Obese patients (Body Mass Index >30)
6.Patients with Hypothyroidism and other endocrinopathies such as Cushingâ??s syndrome
7.Drugs causing derangement of glucose profile
8.Pregnancy
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method 1.To estimate the prevalence of pre-diabetes and diabetes in first degree relatives of type 2 diabetes mellitus patientsTimepoint: at the end of the study
- Secondary Outcome Measures
Name Time Method 1.To assess the insulin resistance in these subjects. <br/ ><br>2.To assess the awareness about lifestyle modifications among these subjects using a validated questionnaire. <br/ ><br>3.To study the effect of lifestyle modifications on their metabolic profile in these subjects in addition to standard drug treatment. <br/ ><br>4.To study the prevalence of TCF7L2 gene polymorphisms in diabetic patients and their first-degree relatives. <br/ ><br>Timepoint: at the end of the study