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临床试验/NCT00164918
NCT00164918Unknown3 期

Role of Routine Nasogastric Decompression After Subtotal Gastrectomy

Chinese University of Hong Kong1 个研究点 分布在 1 个国家目标入组 90 人开始时间: 2004年9月最近更新:
适应症

试验速览

阶段
3 期
入组人数
90
试验地点
1
主要终点
Bowel function and related symptoms early post-op

研究概览

简要总结

The aim of the study is to evaluate whether subtotal gastrectomy without post-operative nasogastric decompression is better in terms of early post-operative bowel function and chest complication.

详细描述

Nasogastric decompression is an intra-operative routine in most of the time to facilitate exposure of operative field during elective subtotal gastrectomy, but whether it should be retained post-operatively is controversial. Nasogastric decompression helps to drain the gastric remnant in case there is edema around the gastrojejunostomy, ileus and delayed gastric emptying, which can theoretically relieve nausea and abdominal distension. Besides, it may help decrease diaphragmatic splintage and hence decrease chance of chest infection if ileus occurs. However, nasogastric intubation could cause patient discomfort; also it has been shown that it would cause gastroesophageal reflux which may be associated with chest complication. There have been studies showing that routine post-operative nasogastric decompression is not necessary for gastrectomy in general, but the role in subtotal gastrectomy for stomach cancer is not well defined.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Parallel
主要目的
Treatment
盲法
None

入排标准

年龄范围
18 Weeks 至 —(Child, Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • All patients suffering from carcinoma of stomach, decided for operation
  • subtotal, D1/D2 dissection
  • palliative resection

排除标准

  • actively bleeding tumor
  • perforation of tumor
  • patient present with gastric outlet obstruction
  • combine organ excision
  • known diabetes with nephropathy

结局指标

主要结局

Bowel function and related symptoms early post-op

次要结局

未报告次要终点

研究者

申办方类型
Other

研究点 (1)

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