Acute neurocognitive effects of Bacopa, Ginseng and Whole Coffee Fruit in healthy adults
试验速览
- 阶段
- 未知
- 状态
- 已完成
- 入组人数
- 40
研究概览
简要总结
This study assessed whether a multi-ingredient herbal supplement containing Bacopa monniera (BM), Panax quinquefolius ginseng (PQ) and Whole Coffee Fruit Extract (WCFE) could enhance cognitive performance and brain activation during tasks of memory and attention. In a randomized, double-blind, placebo-controlled, between-group study, 40 healthy adults between 18-60 years completed cognitive tasks at baseline and following active or placebo supplement consumption in a 2 hour period. During the cognitive testing, changes in brain activity were continuously measured using non-invasive imaging, functional near infrared spectroscopy (fNIRS). The results show significant improvement in tasks of working memory following active supplement consumption compared to placebo and improved performance was associated with changes in amount of brain activity required to complete the task. The results were independent of background demographics variables.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomised controlled trial
- 主要目的
- Prevention
- 盲法
- Blinded (masking used)
入排标准
- 年龄范围
- 18 Years 至 60 Years（—）
- 性别
- All
入选标准
- •Healthy adults aged 18- 60 years, without major medical conditions, such as diabetes,
- •cardiovascular disease, acute or terminal illness; BMI below 35, moderate alcohol consumption, no medication changes for the management of
- •health conditions within last 6 weeks, no current or recent history of taking medications for mood disorders and/or previous history of neurological conditions as these conditions have been shown to be related to impaired cognitive performance.
排除标准
- •Pre-existing medical conditions, including diabetes, cardiovascular disease, medication changes for the management of health conditions within last 6 weeks, current or recent history of taking medications for mood disorders and/or previous history of neurological conditions.