Herbs, Brain Imaging and Memory study.

Not Applicable

Completed

• Conditions: Cognitive performance; Mental Health - Studies of normal psychology, cognitive function and behaviour; Alternative and Complementary Medicine - Herbal remedies

• Registration Number: ACTRN12619001425189
• Lead Sponsor: Central Queensland University

Brief Summary

This study assessed whether a multi-ingredient herbal supplement containing Bacopa monniera (BM), Panax quinquefolius ginseng (PQ) and Whole Coffee Fruit Extract (WCFE) could enhance cognitive performance and brain activation during tasks of memory and attention. In a randomized, double-blind, placebo-controlled, between-group study, 40 healthy adults between 18-60 years completed cognitive tasks at baseline and following active or placebo supplement consumption in a 2 hour period. During the cognitive testing, changes in brain activity were continuously measured using non-invasive imaging, functional near infrared spectroscopy (fNIRS). The results show significant improvement in tasks of working memory following active supplement consumption compared to placebo and improved performance was associated with changes in amount of brain activity required to complete the task. The results were independent of background demographics variables.

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Completion: 2019-03-18
• Study Start: 2019-10-15
• Last Update Posted: 22 October 2019

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 40

Inclusion Criteria

Healthy adults aged 18- 60 years, without major medical conditions, such as diabetes,
cardiovascular disease, acute or terminal illness; BMI below 35, moderate alcohol consumption, no medication changes for the management of
health conditions within last 6 weeks, no current or recent history of taking medications for mood disorders and/or previous history of neurological conditions as these conditions have been shown to be related to impaired cognitive performance.

Exclusion Criteria

Pre-existing medical conditions, including diabetes, cardiovascular disease, medication changes for the management of health conditions within last 6 weeks, current or recent history of taking medications for mood disorders and/or previous history of neurological conditions.

Study & Design

• Study Type: Interventional
• Study Design: Not specified