Effect of Ketamine Co-Induction with Propofol on Body Temperature and Hemodynamics in Neurosurgery: A Randomized Controlled Trial
Not Applicable
Recruiting
- Conditions
- age 18-Male or female,Ketamineᅱ years oldNeurosurgical condition e.g. brain tumor,spinal cord tumorReceive general anesthesia for neurosurgery at least 2 hoursASA (American Society of AnesthesiologisCoinduction,Body Temperature,Hemodynamics,Neurosurgery
- Registration Number
- TCTR20191031003
- Lead Sponsor
- Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 80
Inclusion Criteria
Neurosurgical condition e.g. brain tumor, spinal cord tumor
Receive general anesthesia for neurosurgery at least 2 hours
ASA (American Society of Anesthesiologists) class I - II
Exclusion Criteria
1. Baseline body temperature > 37.3 degree celsius
2. Increased intracranial pressure with Glasgow coma scale (GCS) score < 15
3. Cerebovascular condition e.g. intracerebral aneurysm, arterio-venous malformation
4. Spinal cord injury condition e.g. spinal shock, autonomic hyperreflexia
5. Hypertension both well-controlled and uncontrolled
6. Coronary artery disease
7. Thyrotoxicosis or hyperthyroidism
8. Abnormal autonomic nervous system response
9. obesity (Body mass index > 30 kg/m2)
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Effect of Ketamine Co-Induction with Propofol on Body Temperature every 2-30 minutes depended on the time collecting degree celsius
- Secondary Outcome Measures
Name Time Method Effect of Ketamine Co-Induction with Propofol on Hemodynamics every 2-30 minutes depended on the time collecting mmHg