Acute Effect of Melon Manis Terengganu Peel Powder on Glycemic Response, Satiety, and Food Intake in Adults at Risk for Type 2 Diabetes
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 36
- 试验地点
- 2
- 主要终点
- Blood Glucose Levels
研究概览
简要总结
Open-label, randomised, placebo-controlled, crossover study with two intervention arms. The study was conducted in 30 respondents and the primary objective is to show an improved glycemic response after Melon Manis Terengganu (MMT) peel powder consumption in people at risk of type 2 diabetes.
详细描述
The main aim of the study is to investigate the acute effect of MMT peel powder on glycemic response in people at risk of type 2 diabetes. Besides, the acute effect of MMT peel powder on perceived satiety and energy intake were explored.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Basic Science
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 59 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Modified Finnish Type 2 Diabetes Risk Assessment Tool (FINDRISC) score ≥ 4
- •Capillary fasting blood glucose (FBG) < 7.0 mmol/L
- •Malaysian
- •Live, work or study in Kuala Nerus, Terengganu
- •Both gender
- •Age 18 to 59 years old
- •Non-smoker
- •Those taking supplement agree to undergo washout period of one week
排除标准
- •Had clinical history of type 2 diabetes mellitus (T2DM)
- •Capillary FBG ≥ 7.0 mmol/L
- •Take oral antidiabetic agents
- •Participate in other weight management programme or interventional research
- •On a prescribed medical diet
- •GI illnesses or conditions
- •Allergy or sensitivity to study products
- •Pregnant, currently breastfeeding, or planning to become pregnant
- •On dietary restrictions
结局指标
主要结局
Blood Glucose Levels
时间窗: Baseline (0 min), 30, 60, 90 and 120 minutes on Day 1 and Day 4 of both study visits
Blood glucose were measured using glucometer (Accu Chek Performa, New South Wales, Australia) from finger-prick blood samples according to the standard operating procedure at baseline (0 min), 30, 60, 90 and 120 minutes.
次要结局
- Perceived Satiety (Area Under the Curve)(Day 1 and 4 of both study visits)
- Food Intake(Day 1 and 4 of both study visits)
- Calories Intake(Day 1 and day 4 of both study visits)
研究者
Ong Ying Qian
Principal Investigator
Universiti Sultan Zainal Abidin