Quantitative assessment of the clitoral sexual arousal response in pre and postmenopausal women using magnetic resonance imaging

Recruiting

Conditions: sexual (dys)function
sexual (dys)functioning
10013356

Registration Number: NL-OMON53425

Lead Sponsor: Amsterdam UMC

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Recruiting

Sex: Not specified

Target Recruitment: 24

Inclusion Criteria

In order to be eligible to participate in this study, a subject must meet all
of the following criteria:
- Adult, >18 years of age
- Able to give written informed consent
- Having a primarily heterosexual orientation
- Having a stable, sexually active relationship for at least the preceding 6
months

In addition, for premenopausal women:
- Age < 45 and having a regular menstrual cycle.

In addition, for postmenopausal women:
- Age > 45 years, and no menstruation since at least one year, after a
previously regular menstrual cycle. No use, or recent (in the prior 6 months)
use of estrogen, hormonal medication, or hormonal contraception.

Exclusion Criteria

- Use, or recent (in the prior 6 months) use, of psychotropic medication
- Acute or chronic medical or mental conditions with a known effect on sexual
response
- Current pregnancy or delivery within the last 12 months
- History of hysterectomy or vaginal surgery, gynecologic disease or
malignancy, pelvic inflammatory disease or vaginal infection and known
anatomical abnormalities of the genitalia.
- Contra-indications to MRI (metal implants, pacemakers, claustrophobia, etc.).

Study & Design

Study Type: Observational non invasive

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>The primary endpoint is clitoral volume during sexual arousal assessed by MRI<br /><br>in healthy pre and postmenopausal women.</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>Secondary endpoints are self-reported feelings of sexual arousal during<br />audiovisual sexual stimulation (erotic film), and sexual function assessed by a<br />validated sexual function questionnaire with the addition of items about<br />orgasmic functioning.</p>