NCT05537974已完成不适用
Effect of Endotracheal Aspiration on End-expiratory Lung Volume in Patients With ARDS, Comparison of Open vs. Closed Suction, A Randomize Cross-over Study
Izmir Dr Suat Seren Chest Diseases and Surgery Education and Research Hospital2 个研究点 分布在 1 个国家目标入组 20 人开始时间: 2022年9月15日最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 20
- 试验地点
- 2
- 主要终点
- End expiratory lung volume (EELV)
研究概览
简要总结
The alveoli tend to collapse in patients with ARDS. Endotracheal aspiration may increase alveolar collapse by decreasing the end-expiratory lung volume. The hypothesis is that closed endotracheal aspiration led to less end-expiratory volume loss when compared to open endotracheal aspiration.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Screening
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Mechanically ventilated due to ARDS
排除标准
- •Hemodynamically unstable Air leaks syndrome (pneumothorax) Higher level of FiO2 (>60%) Chronic obstructive pulmonary disease
结局指标
主要结局
End expiratory lung volume (EELV)
时间窗: One minute before suctioning, 1, 10, 20, 30 minutes after suctioning
End expiratory lung impedance (EELI) will be measured wit electric impedance tomography. Change in EELI representative of change in EELV.
次要结局
未报告次要终点
研究者
Cenk Kirakli, M.D.
Professor Doctor
Izmir Dr Suat Seren Chest Diseases and Surgery Education and Research Hospital
研究点 (2)
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