Effects of Surgical Correction of Nasal Obstruction on Oxygen Uptake and Ventilation Volume
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 22
- 主要终点
- Change in Running Economy (ml/kg/min)
研究概览
简要总结
This retrospective study aims to evaluate the effect of surgical correction of nasal obstruction on aerobic performance parameters in male athletes aged 20-32 years. The main questions it aims to answer are:
- Does nasal obstruction surgery impact running economy and ventilation during exercise?
- Does it affect oxygen consumption during submaximal running efforts?
Researchers will retrospectively compare male athletes who underwent nasal obstruction surgery (experimental group) to matched athletes without nasal obstruction (control group) to assess changes in respiratory function and exercise performance.
Participants were assessed by:
- Acoustic rhinometry to measure nasal cavity dimensions.
- The Nasal Obstruction Symptom Evaluation (NOSE) scale and Epworth Sleepiness Scale (ESS) to evaluate nasal obstruction symptoms and daytime sleepiness.
- Incremental treadmill exercise tests to collect data on gas exchange, oxygen consumption, ventilation, and running economy before and after the surgical intervention (or across a similar time period for the control group).
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- None
盲法说明
This study was conducted without masking. Participants and investigators were aware of group assignments due to the nature of the intervention (surgical septoplasty). Outcome assessments (aerobic performance tests and symptom questionnaires) were conducted using objective measures and standardized procedures to minimize bias.
入排标准
- 年龄范围
- 18 Years 至 40 Years（Adult）
- 性别
- Male
- 接受健康志愿者
- 是
入选标准
- •For Experimental Group (EG):
- •Diagnosed with nasal obstruction due to septal deviation and/or inferior turbinate hypertrophy
- •Experiencing nasal breathing difficulties and sleep disturbance
- •Deemed eligible for septoplasty and/or inferior turbinoplasty following physical and endoscopic examination
- •Voluntarily agreed to participate in the study
- •For Control Group (CG):
- •No reported nasal obstruction or breathing complications
- •Matched with EG participants by age, sport discipline, training level, and VO₂max (with a maximum variation of ±5%)
- •Willing to follow a similar training program to their matched EG counterparts between pre- and post-testing periods
排除标准
- •History of nasal surgery
- •Presence of cardiopulmonary diseases
- •Musculoskeletal disorders affecting physical performance or exercise testing
- •Inability or unwillingness to follow the pre- and post-test training schedule
- •Any surgical complication that would interfere with post-operative participation in physical testing (note: none occurred in this study)
研究组 & 干预措施
Athletes Undergoing Septoplasty (EG)
This arm included male athletes diagnosed with nasal obstruction who underwent surgical correction via septoplasty. Participants were evaluated before and approximately 2-3 months after surgery. Assessments included acoustic rhinometry to measure nasal cavity cross-sectional areas and volumes, the Epworth Sleepiness Scale (ESS), and the Nasal Obstruction Symptom Evaluation (NOSE) scale. Aerobic performance parameters such as running economy, oxygen consumption, and ventilation volume were measured using an incremental treadmill test and respiratory gas analysis.
干预措施: Surgical correction of nasal obstruction (Procedure)
Control Group
Male athletes without nasal obstruction, matched by age and training level with the experimental group. They did not receive any intervention but underwent the same aerobic performance testing protocol at the same time points for comparison.
结局指标
主要结局
Change in Running Economy (ml/kg/min)
时间窗: Baseline and 2-3 months post-surgery
Running economy was assessed via an incremental treadmill test by measuring steady-state oxygen consumption (VO₂) at submaximal running speeds (e.g., 8, 10, 12 km/h). Improvement in running economy is defined by a decrease in VO₂ at the same speed, indicating greater efficiency.
次要结局
- Change in Oxygen Consumption (VO₂ max and submax VO₂)(Baseline and 2-3 months post-surgery)
- Change in Ventilation(Baseline and 2-3 months post-surgery)
研究者
Tuba Melekoğlu
Assoc. Prof.
Akdeniz University