NCT01818895已完成不适用
Terminal Weaning of Mechanical Ventilation or Extubation in Anticipation of Death in the Intensive Care Unit: Impact on Relatives, Care Givers and the Dying Process - A Prospective, Multicenter, Observational Study
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 458
- 试验地点
- 44
- 主要终点
- Post traumatic Stress Disorder
研究概览
简要总结
The purpose of the study is to assess the dying process in critically ill patients with decision to withdraw invasive mechanical ventilation in anticipation of death and to compare effects of extubation and those of terminal weaning of mechanical ventilation on relatives and care givers. The investigators primary hypothesis is that extubation is associated with less symptoms of post-traumatic stress disorders in relatives, as compared to terminal weaning.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •End of life decision to withdraw invasive mechanical ventilation after at least 48 hours of ICU stay
排除标准
- •Age under 18 years
- •Non invasive mechanical ventilation
- •Brain death
- •Death before withdrawal of mechanical ventilation
- •No French-speaking relative
- •Refusal of relative to participate the study
结局指标
主要结局
Post traumatic Stress Disorder
时间窗: three month after patient's death
Post traumatic Stress Disorder as assessed by the Impact of event Scale-revised(IES-R)
次要结局
- Complicated grief(6 and 12 months after patient's death)
- Burn out syndrome of the physician(within day 1 after patient's death)
- Post traumatic Stress Disorder(12 months after patient's death)
- Relative's satisfaction(3 months after patient's death)
- Physician's satisfaction(within day 1 after patient's death)
- Burn out syndrome of the nurse(within day 1 after patient's death)
- Anxiety and depression(3, 6 and 12 months after patient's death)
- Nurse's satisfaction(within day 1 after patient's death)
研究者
研究点 (44)
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