NCT01818895
Completed
N/A
Terminal Weaning of Mechanical Ventilation or Extubation in Anticipation of Death in the Intensive Care Unit: Impact on Relatives, Care Givers and the Dying Process - A Prospective, Multicenter, Observational Study
Overview
- Phase
- N/A
- Intervention
- Not specified
- Conditions
- Withdrawal
- Sponsor
- Centre Hospitalier Departemental Vendee
- Enrollment
- 458
- Locations
- 44
- Primary Endpoint
- Post traumatic Stress Disorder
- Status
- Completed
- Last Updated
- 10 years ago
Overview
Brief Summary
The purpose of the study is to assess the dying process in critically ill patients with decision to withdraw invasive mechanical ventilation in anticipation of death and to compare effects of extubation and those of terminal weaning of mechanical ventilation on relatives and care givers. The investigators primary hypothesis is that extubation is associated with less symptoms of post-traumatic stress disorders in relatives, as compared to terminal weaning.
Investigators
Eligibility Criteria
Inclusion Criteria
- •End of life decision to withdraw invasive mechanical ventilation after at least 48 hours of ICU stay
Exclusion Criteria
- •Age under 18 years
- •Non invasive mechanical ventilation
- •Brain death
- •Death before withdrawal of mechanical ventilation
- •No French-speaking relative
- •Refusal of relative to participate the study
Outcomes
Primary Outcomes
Post traumatic Stress Disorder
Time Frame: three month after patient's death
Post traumatic Stress Disorder as assessed by the Impact of event Scale-revised(IES-R)
Secondary Outcomes
- Complicated grief(6 and 12 months after patient's death)
- Burn out syndrome of the physician(within day 1 after patient's death)
- Post traumatic Stress Disorder(12 months after patient's death)
- Relative's satisfaction(3 months after patient's death)
- Physician's satisfaction(within day 1 after patient's death)
- Burn out syndrome of the nurse(within day 1 after patient's death)
- Anxiety and depression(3, 6 and 12 months after patient's death)
- Nurse's satisfaction(within day 1 after patient's death)
Study Sites (44)
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