15-year Mortality After Hospitalization for Exacerbation of Chronic Obstructive Pulmonary Disease

Completed

• Conditions: Exacerbation Copd; Mortality; Chronic Obstructive Pulmonary Disease

• Registration Number: NCT02972775
• Lead Sponsor: Zuyderland Medisch Centrum

Brief Summary

The investigators examine the 15-year mortality after an admission for an exacerbation of Chronic Obstructive Pulmonary disease (COPD).

Detailed Description

Several prognostic factors will be examined. Cause of death will be examined. Data will be recruited from medical records and calling general practitioners to find out if a patient is still alive. Statistical analysis will be done with Kaplan Meier, Cox proportional hazards and Chi square

Study Timeline

• Study Start: 2005-01
• Study First Submitted: 2016-10-24
• Study First Submitted QC: 2016-11-20
• Study First Posted: 2016-11-23
• Primary Completion: 2017-10
• Study Completion: 2017-10
• Status Verified: 2020-06
• Last Update Submitted: 2020-06-02
• Last Update Posted: 2020-06-04

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 845

Inclusion Criteria

• admission with exacerbation of COPD

Exclusion Criteria

• none

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Percentage of patients that died after 15 years	15 years	Mortality after 15 years

Secondary Outcome Measures

Name	Time	Method
Prognostic factors for mortality	15 years	Age (years), Gender (M / F), Previous hospitalization in the past year (yes/no), Re-admission in the next 5 years (number of readmissions per year), forced expiratory volume in 1 second (in liter), Hypercapnia (carbon dioxide in arterial blood in stable condition above 5.9 kiloPascal (kPa) or not), TLCO (transfusion capacity of the lung for carbon monoxide in percentage of predicted, ml / min / kPa), Comorbidity (Charlson Comorbidity Index) Date and cause of death
Cause of death	15 years	Chronic obstructive pulmonary disease, lung carcinoma, cardiovascular, other

Trial Locations

Locations (1)

Zuyderland Medical Center; 🇳🇱 Heerlen, Limburg, Netherlands