Molecular Characterization of Carbapenemase-Producing Enterobacterales Isolated From Clinical Samples in Egypt
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 入组人数
- 100
- 试验地点
- 1
- 主要终点
- Isolation of causative organism
研究概览
简要总结
Bacterial infections with carbapenem resistant pathogens are one of the major threats in immunocompromised patients, especially among cancer patients .Furthermore, Gram negative pathogens are becoming increasingly prevalent and have become an ongoing global health concern .Emergence of Gram-negative pathogens, especially Enterobacterales that avert many of the human defense mechanisms are alarmingly increasing and most of these pathogens are resistant to many of the in-use antibiotics including carbapenems .
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Screening
- 盲法
- Triple (Participant, Investigator, Outcomes Assessor)
入排标准
- 年龄范围
- 4 Years 至 80 Years（Child, Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •All patients admitted to Sohag Oncology Center have different infections and isolated organism one of carbapenem resistant enterobacterales detected by antibiotic sensitivity test.
排除标准
- •All patients admitted to Sohag Oncology Center having infections in different sites and isolated organisms are not one of enterobacterales and not carbapenem resistant.
研究组 & 干预措施
Group 1 Patients with enterobacterials infections
干预措施: Antibiotic administration (Diagnostic Test)
Group 1 Patients with enterobacterials infections
干预措施: Molecular detection of antibiotic resistance (Diagnostic Test)
Group 2 patients with other bacterial infections
干预措施: Antibiotic administration (Diagnostic Test)
Group 2 patients with other bacterial infections
干预措施: Molecular detection of antibiotic resistance (Diagnostic Test)
结局指标
主要结局
Isolation of causative organism
时间窗: 6 months
次要结局
- Antibitic sensitivity test:(2 months)
- Molecular detection of carbapenem resistant genes:(3 months)
研究者
Noha Saber Shafik
assistant professor
Sohag University