Effects of Cistanche Supplementation on Anaerobic Exercise Performance and Recovery in Men With Different Athletic Training Levels: A Double-Blind, Randomized, Placebo-Controlled Trial
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 56
- 试验地点
- 1
- 主要终点
- Peak power during the 30-second Wingate Anaerobic Test
研究概览
简要总结
This study is a double-blind, randomized, placebo-controlled trial designed to examine whether 8 weeks of Cistanche deserticola supplementation, when combined with a standardized anaerobic training program, can improve anaerobic exercise performance, recovery, and selected body composition outcomes in young adult men with different athletic training levels.
Participants will be assigned to receive either Cistanche deserticola extract or a matched placebo while completing the same supervised anaerobic training program. The study will assess changes in anaerobic performance, including Wingate test outcomes and jump performance, as well as recovery-related indicators such as blood lactate, creatine kinase, malondialdehyde, testosterone, cortisol, and the testosterone-to-cortisol ratio. Body composition outcomes, including body fat percentage and skeletal muscle mass, will also be evaluated.
The purpose of this study is to determine whether Cistanche deserticola supplementation provides additional benefits beyond training alone, and whether these effects differ between highly trained and recreationally trained participants.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Health Services Research
- 盲法
- Double (Participant, Investigator)
盲法说明
Masking Description
入排标准
- 年龄范围
- 18 Years 至 25 Years（Adult）
- 性别
- Male
- 接受健康志愿者
- 是
入选标准
- •Male, aged 18 to 25 years
- •Body mass index (BMI) between 18.5 and 25.0 kg/m²
- •Able and willing to provide written informed consent
- •Willing to comply with study procedures, supplementation, training, and assessments
- •Belonging to one of the following athletic training strata:
- •High-level elite stratum: Chinese National Level-1 Athlete standard in sprint-related events, regular training in past 12 months and active during study
- •Amateur stratum: regular exercise-training background in past 12 months without National Level-1 status
排除标准
- •Use of steroids or ergogenic supplements during study
- •Known cardiovascular, metabolic, musculoskeletal, or other conditions making participation unsafe or affecting outcomes
- •Current use of medications affecting muscle growth, recovery, hormones, or high-intensity performance
- •Current injury or limitation preventing safe participation
- •Known allergy or intolerance to supplement/placebo ingredients
- •Participation in another clinical trial or structured intervention during study period
- •Inability or unwillingness to comply with protocol
- •Any other condition deemed unsuitable by investigators
研究组 & 干预措施
Cistanche Supplementation + Standardized Anaerobic Training
Participants in this arm receive Cistanche deserticola extract paste (5 g/day) for 8 weeks while completing the same supervised standardized anaerobic training program as the control arm. The training program is performed 3 times per week and includes repeated sprint training, explosive/strength-support exercises, and short-bout high-intensity interval training.
干预措施: Standardized anaerobic training program (Behavioral)
Cistanche Supplementation + Standardized Anaerobic Training
Participants in this arm receive Cistanche deserticola extract paste (5 g/day) for 8 weeks while completing the same supervised standardized anaerobic training program as the control arm. The training program is performed 3 times per week and includes repeated sprint training, explosive/strength-support exercises, and short-bout high-intensity interval training.
干预措施: Cistanche deserticola (Dietary Supplement)
Placebo + Standardized Anaerobic Training
Participants in this arm receive a matched placebo for 8 weeks while completing the same supervised standardized anaerobic training program as the experimental arm. The placebo is matched in appearance, weight, texture, and taste. The training program is performed 3 times per week and includes repeated sprint training, explosive/strength-support exercises, and short-bout high-intensity interval training.
干预措施: Matched placebo paste (Dietary Supplement)
Placebo + Standardized Anaerobic Training
Participants in this arm receive a matched placebo for 8 weeks while completing the same supervised standardized anaerobic training program as the experimental arm. The placebo is matched in appearance, weight, texture, and taste. The training program is performed 3 times per week and includes repeated sprint training, explosive/strength-support exercises, and short-bout high-intensity interval training.
干预措施: Standardized anaerobic training program (Behavioral)
结局指标
主要结局
Peak power during the 30-second Wingate Anaerobic Test
时间窗: Baseline (week 0) and post-intervention (week 8)
Peak power (W) measured during a 30-second Wingate Anaerobic Test performed on a Monark 894E cycle ergometer. The test is conducted under standardized conditions, and the primary analysis will evaluate the change from baseline to post-intervention and the between-group difference in change after 8 weeks of intervention.
Squat jump height
时间窗: Baseline (week 0) and post-intervention (week 8)
Squat jump (SJ) height in centimeters, assessed under standardized testing conditions as a measure of lower-limb explosive performance. Analyses will assess change from baseline to post-intervention and between-group differences in change.
Countermovement jump
时间窗: Baseline (week 0) and post-intervention (week 8)
Countermovement jump (CMJ) height in centimeters, assessed under standardized testing conditions as a measure of lower-limb explosive performance. Analyses will assess change from baseline to post-intervention and between-group differences in change.
次要结局
- Average power during the 30-second Wingate Anaerobic Test(Baseline (week 0) and post-intervention (week 8))
- Minimum power during the 30-second Wingate Anaerobic Test(Baseline (week 0) and post-intervention (week 8))
- Power drop during the 30-second Wingate Anaerobic Test(Baseline (week 0) and post-intervention (week 8))
- Post-exercise blood lactate response(Baseline (week 0) and post-intervention (week 8))
- Serum creatine kinase concentration(Baseline (week 0) and post-intervention (week 8))
- Serum malondialdehyde concentration(Baseline (week 0) and post-intervention (week 8))
- Serum testosterone concentration(Baseline (week 0) and post-intervention (week 8))
- Body fat percentage(Baseline (week 0) and post-intervention (week 8))
- Skeletal muscle mass(Baseline (week 0) and post-intervention (week 8))
- Serum cortisol concentration(Baseline (week 0) and post-intervention (week 8))