Clinical effect of three additional methods (two antimicrobial photodynamic therapy systems and chlorhexidine) to non-surgical treatment of peri-implantitis: a randomized prospective study
Phase 4
- Conditions
- Peri-implantitis
- Registration Number
- DRKS00011171
- Lead Sponsor
- Klinik für Mund-, Kiefer- und Gesichtschirurgie, Plastische Operationen
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 30
Inclusion Criteria
Inclusion criteria have been a peri-implantitis, which were not treated before with probing depth (PD) > 5 mm, bleeding on probing (BoP) and bone loss in the x-ray
Exclusion Criteria
Exclusion criteria have been to maintain therapy or to receive peri-implant treatment during the last six months; using antimicrobials (systemic or topical), anti-inflammatory or immunosuppressive drugs during the three months preceding the study
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Clinical (bleeding on probing (BoP), pus, modified plaque index, pocket depth (PD), and crevicular fluid) mikrobiological parameters after three month. measurement of bleeding on probing at 6 probing points with a periodontal probe. Pus registration out of the sulcus was measured clinical. The modified plaque indes of Sillnes and Loe was used. To measure the pocket probing depth a periodontal probe was used. The sulks fluid was measured using blotting paper. The concentration of alpha MMP-8 was examined using a kitten (diagnostika) and the periodontal pathogens have been identified from the company (Hain Life science, MicroIdentPlus).<br><br>
- Secondary Outcome Measures
Name Time Method clinical and microbiological parameter from E1-E5