EmploYEd Antithrombotic Therapies in Patients With Acute Coronary Syndromes HOspitalized in iTalian CCUs
- Conditions
- Acute Coronary Syndrome
- Registration Number
- NCT06316128
- Lead Sponsor
- Heart Care Foundation
- Brief Summary
This registry has the aim to assess the use of different antithrombotic therapies, including untested drug combinations, routinely used during the hospitalization phase, with their timing, route and dose of administration, in consecutive patients discharged with a diagnosis NSTEMI or STEMI in Italian Cardiac care Units (CCUs) during a four-week study period.
- Detailed Description
EYESHOT-2 is a prospective, multicenter, observational, nationwide survey of patients discharged with a diagnosis NSTEMI or STEMI admitted to Italian CCUs.
The survey will be designed to include all consecutive patients, who met the eligibility criteria, admitted in hospitals with or without cardiac catheterization laboratories and cardiac surgery facilities during a period of 4 weeks.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 2806
- All consecutive patients aged 18 years or more, discharged with diagnosis of myocardial infarction (NSTEMI or STEMI) admitted to CCUs undergoing myocardial revascularization (PCI or CABG) or conservative treatment. At presentation, the diagnosis of NSTEMI will be based on the measurement of troponins and assessment of ECG changes, as suggested by European Society of Cardiology (ESC) guidelines; the diagnosis of STEMI will be characterized by an acute chest pain and persistent (>20 min) ST-segment elevation ≥ 1mm in two or more limb leads, or contiguous pre-cordial leads or left bundle branch block.
- Written informed consent signed. Patients who cannot provide the informed consent due to very severe clinical conditions can give their consent some hours/days after admission, when more favourable clinical conditions allow them to receive the appropriate information. Patients having died before giving informed consent may also be included unless the local Institutional Review Board (IRB) does not allow this procedure. In that case, it is strongly suggested to obtain relative(s) agreement through the collect of a signed informed consent.
- Patients with a diagnosis of Unstable Angina,
- Patients developing MI after PCI or CABG,
- MI following non-cardiac surgery or traumatic causes,
- Patients with chest pain without elevation of troponin,
- Patients enrolled in Randomized Controlled Trial (RCTs),
- Patients already enrolled into the study from another CCU
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Antithrombotic therapies 1 week The primary objective of the study is to describe at a national level the different antithrombotic therapies (alone or in combination) commonly employed from admission to discharge in NSTEMI or STEMI patients undergoing different therapeutic strategies (PCI, CABG, conservative). A particular focus will be given to antithrombotic therapies (combinations, timing of administration, indications) used (a) before PCI (pre-treatment) (b) in the cath lab during PCI \[use of Glycoprotein IIb/IIIa inhibitors (GPIs), cangrelor, anticoagulants\] and (c) during hospital stay.
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (188)
Ospedale Santo Spirito - Sc Cardiologia
🇮🇹Casale, AL, Italy
Ospedali Riuniti - Sod Cardiologia Ospedaliera E Utic
🇮🇹Ancona, AN, Italy
Irccs Inrca - Uo Cardiologia/Utic/Telecardiologia
🇮🇹Ancona, AN, Italy
Ospedale San Donato - U.O.C Cardiologia
🇮🇹Arezzo, AR, Italy
Ospedale Valdarno S. Maria Della Gruccia - U.O. Malattie Cardiovascolari
🇮🇹Montevarchi, AR, Italy
Aorn San Giuseppe Moscati - U.O. Cardiologia/Utic 'D. Rotiroti'
🇮🇹Avellino, AV, Italy
Ospedale Miulli - U.O.C. Cardiologia - Utic
🇮🇹Acquaviva Delle Fonti, BA, Italy
Ospedale Della Murgia - Fabio Perinei - S.C. Cardiologia-Utic
🇮🇹Altamura, BA, Italy
Ospedale San Paolo - Cardiologia-Utic
🇮🇹Bari, BA, Italy
Aou Policlinico - Uoc Cardiologia Ospedaliera
🇮🇹Bari, BA, Italy
Scroll for more (178 remaining)Ospedale Santo Spirito - Sc Cardiologia🇮🇹Casale, AL, Italy