Evaluation of the Efficacy and Safety of Suppressive Therapy With DALBAVANCINE in Device Infections
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 15
- 试验地点
- 1
- 主要终点
- efficacy of suppressive Dalbavancin therapy
研究概览
简要总结
The aim of this retrospective observational study is to evaluate the efficacy of antibiotic therapy with dalbavancin in patients presenting with infection on prosthetic devices. The main questions the study aims to answer are:
What is the proportion of patients with early discontinuation of dalbavancin therapy? What are the reasons for early discontinuation of antibiotic treatment? What adverse events do patients report? The study is based on data collected as part of routine care practices.
Translated with www.DeepL.com/Translator (free version)
研究设计
- 研究类型
- Observational
- 观察模型
- Case Only
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients with inextricable and/or inoperable osteoarticular or vascular prosthetic material.
- •Patients requiring suppressive antibiotic therapy (>6 months) with dalbavancin.
排除标准
- •Patients who are protected adult;
- •Patients who are minors;
- •Patients having expressed their opposition
结局指标
主要结局
efficacy of suppressive Dalbavancin therapy
时间窗: two-year follow-up after initiation of suppressive therapy with Dalbavancin
Proportion of patients successfully treated with Dalbavancin. The efficacy of suppressive therapy will be defined over a two-year period after initiation of treatment as the combination of the following criteria: Clinical control of infection : * Absence of local inflammatory signs (erythema, discharge, edema, pain) ; * Absence of general signs (hyperthermia: T°\>38 or hypothermia T°\< 36°); Biological control: o CRP negative (\<5mg/l) ;
次要结局
未报告次要终点