Identification of optimal urine and blood biomarkers of acute kidney injury (AKI) in patients with Acute Decompensated Heart Failure (ADHF)

Christchurch Heart Institute Trust0 个研究点目标入组 86 人开始时间: 2015年9月11日最近更新: 2021年6月21日

适应症

试验速览

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•Provide signed and dated informed consent form
•Willing to comply with all study procedures and be available for the duration of the study
•Living independently (ie, not hospital care dependent)
•Admitted with ADHF as evidenced by typical clinical features plus either radiological evidence of HF or an NTproBNP level >1000pg/ml.

•A primary diagnosis of acute coronary syndrome (ACS), myocarditis/pericarditis, pericardial constriction,
•A life expectancy due to non-cardiac disease of <6 months,
•A concurrent severe hepatic or pulmonary disease A concurrent severe hepatic disease
•Severe renal impairment (plasma creatinine >250 micromol/L),
•Severe valvular disease requiring surgery,
•Severe aortic stenosis (valve area <1 cm^2), or HF due to mitral stenosis
•A patient under consideration for cardiac transplantation
•Without a urine sample within 4 hours of admission
•With a prior eGFR <15 ml/min/1.73m2
•On dialysis
•Unable to comply with study protocol requirements
•Unwilling or unable to consent
•Already actively enrolled in this study

发起方