Association Between Food/Nutrient Intake and Sleep Quality in Middle Aged and Older Population
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 108
- 试验地点
- 1
- 主要终点
- Sleep Quality Assessment 1 (Sleep Efficiency)
研究概览
简要总结
Sleep is essential to health. Quality of sleep, measure through indexes of sleep, is related to the incidence of obesity, type 2 diabetes, cardiovascular disease, hypertension, and premature death. Sleep pattern changes as people age. They tend to have a harder time falling asleep and more trouble staying asleep than when they were younger. Studies have shown that food/nutrient intake may be associated with sleep duration, quality, and patterns. Singapore's population is aging rapidly and improving their indexes of sleep may result in their health promotion.
详细描述
Sleep is essential to health and indexes of sleep including duration, quality, and patterning are related to the incidence of chronic diseases and premature death. Changes in sleep patterns are a part of the aging process and as people age, they tend to have a harder time falling asleep and more trouble staying asleep than when they were younger. Certain cross-sectional studies have shown that food/nutrient intake may be associated with sleep duration, quality, and patterns. In the last decade, Singapore's population has grown older. However, limited research examined the association between food/nutrient intake and indexes of sleep in middle-aged and older population in Singapore. Therefore, with a growing number of elderly, studies on improving their sleep quality can play a significant role in improving their quality of life. This is a cross-sectional study and subjects require a 1-day visit (one time visit ONLY). Generally healthy middle-aged and older population will be recruited and after the phone screening and validated subjects will complete the medical history questionnaire and to be brought on the day of visit. During the visit, subjects will stay approximately 3-h to complete the testing. After completing the consent form, fasting-state blood collection and general health assessment will be conducted. Then subjects will be asked to complete the questionnaires to assess sleep quality and dietary intake.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Cross Sectional
入排标准
- 年龄范围
- 50 Years 至 75 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Ability to give an informed consent
- •Age 50 to 75 years
- •Not taking dietary supplements which may impact the outcome of the interests (I.e. dietary protein and vitamin supplements)
- •Not having significant dietary changes for the past 1 year (i.e. weight loss, vegetarian diet)
- •Having sufficient venous access to allow the blood collection
- •Willing to follow the study procedure
排除标准
- •Unable to give an informed consent
- •Age < 50 years
- •Taking dietary supplements which may impact the outcome of the interest (i.e. dietary proteins and vitamin supplements)
- •Having/had significant dietary changes for the past 1 year
- •Not having sufficient venous access to allow the blood collection
- •Unwilling to follow the study procedure
结局指标
主要结局
Sleep Quality Assessment 1 (Sleep Efficiency)
时间窗: Day 1
Pittsburgh sleep quality index (PSQI) Sleep efficiency (%)
Sleep Quality Assessment 2
时间窗: Day 1
Sleep evaluation questionnaire Score: 0-56 (arbitrary unit) Lower score suggests better sleep
Dietary Assessment 2 (Dietary Carotenoids)
时间窗: Day 3
3 Day 24-Hr Dietary Recall: Participants will be given a diagram showing serving sizes that they can refer to for measurements. Only 3 out of the 7 days of the week are required for the participants to record their food intake. Results are reported as the average value of the analysed nutrients (dietary carotenoids) across the 3 days the dietary data was collected.
Sleep Quality Assessment 1 (Sleep Duration)
时间窗: Day 1
Pittsburgh sleep quality index (PSQI) Sleep duration (hours)
Dietary Assessment
时间窗: Day 1
Food Frequency Questionnaire (FFQ)
Blood Amino Acid Concentration (Plasma Tryptophan)
时间窗: Day 1
Amino acid analysis on collected blood serum for blood amino acid profile.
Dietary Assessment 2 (Dietary Macronutrients)
时间窗: Day 3
3 Day 24-Hr Dietary Recall: Participants will be given a diagram showing serving sizes that they can refer to for measurements. Only 3 out of the 7 days of the week are required for the participants to record their food intake. Results are reported as the average value of the analysed nutrients (dietary fat) across the 3 days the dietary data was collected.
Sleep Quality Assessment 1 (GSS)
时间窗: Day 1
Pittsburgh sleep quality index (PSQI) Global Sleep Score (GSS): 0-21 (arbitrary unit; au) A lower value indicates better sleep quality
Sleep Quality Assessment 1 (Sleep Latency)
时间窗: Day 1
Pittsburgh sleep quality index (PSQI) Sleep latency (minutes)
次要结局
- Anthropometric Measurements 1(Day 1)
- Anthropometric Measurements 2(Day 1)
- Blood Pressure(Day 1)
- Blood Lipid and Glucose Profile(Day 1)
- Plasma Carotenoids Concentration(Day 1)
- Anthropometric Measurements 3(Day 1)
- Skin Carotenoid Status(Day 1)
- Perceived Stress Assessment(Day 1)
研究者
Jung Eun Kim
Assistant Professor
National University of Singapore